Detailed information NTG0143687

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ASL18_RS09650
• Genome accession: NZ_CP013959
• Coordinates: 1919426..1920415 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain V605 isolate sequencing
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1914426..1925415

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASL18_RS09635 (ASL18_09640)	acsA	1915627..1917333 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
ASL18_RS09640 (ASL18_09645)	-	1917502..1918134 (+)	633	WP_063456418.1	hypothetical protein	-
ASL18_RS09645 (ASL18_09650)	-	1918159..1919328 (+)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
ASL18_RS09650 (ASL18_09655)	ccpA	1919426..1920415 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
ASL18_RS09655 (ASL18_09660)	-	1920488..1920601 (-)	114	WP_001788994.1	hypothetical protein	-
ASL18_RS09660 (ASL18_09665)	-	1920955..1922046 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
ASL18_RS09665 (ASL18_09670)	-	1922507..1922611 (-)	105	WP_001791758.1	hypothetical protein	-
ASL18_RS09670 (ASL18_09675)	-	1922746..1924104 (-)	1359	WP_000193917.1	hypothetical protein	-
ASL18_RS09675 (ASL18_09680)	-	1924178..1924669 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=143687 ASL18_RS09650 WP_000219066.1 1919426..1920415(-) (ccpA) [Staphylococcus aureus strain V605 isolate sequencing]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=143687 ASL18_RS09650 WP_000219066.1 1919426..1920415(-) (ccpA) [Staphylococcus aureus strain V605 isolate sequencing]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462