Detailed information NTG0143595

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ASL17_RS09335
• Genome accession: NZ_CP013957
• Coordinates: 1877145..1878134 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain V521 isolate Sequencing
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1872145..1883134

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASL17_RS09320 (ASL17_09325)	acsA	1873346..1875052 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
ASL17_RS09325 (ASL17_09330)	-	1875221..1875853 (+)	633	WP_001015996.1	hypothetical protein	-
ASL17_RS09330 (ASL17_09335)	-	1875878..1877047 (+)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
ASL17_RS09335 (ASL17_09340)	ccpA	1877145..1878134 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
ASL17_RS09340 (ASL17_09345)	-	1878207..1878320 (-)	114	WP_001788994.1	hypothetical protein	-
ASL17_RS09345 (ASL17_09350)	-	1878674..1879765 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
ASL17_RS09350 (ASL17_09355)	-	1880226..1880330 (-)	105	WP_001791758.1	hypothetical protein	-
ASL17_RS09355 (ASL17_09360)	-	1880465..1881823 (-)	1359	WP_000193917.1	hypothetical protein	-
ASL17_RS09360 (ASL17_09365)	-	1881897..1882388 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=143595 ASL17_RS09335 WP_000219066.1 1877145..1878134(-) (ccpA) [Staphylococcus aureus strain V521 isolate Sequencing]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=143595 ASL17_RS09335 WP_000219066.1 1877145..1878134(-) (ccpA) [Staphylococcus aureus strain V521 isolate Sequencing]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462