Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AWH44_RS12365 Genome accession   NZ_CP013952
Coordinates   2404215..2404847 (-) Length   210 a.a.
NCBI ID   WP_001698625.1    Uniprot ID   -
Organism   Escherichia coli strain HST04     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2399215..2409847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWH44_RS12340 (AWH44_11840) yhfG 2399347..2399514 (+) 168 WP_000736862.1 YhfG family protein -
  AWH44_RS12345 (AWH44_11845) fic 2399504..2400106 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  AWH44_RS12350 (AWH44_11850) pabA 2400138..2400701 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AWH44_RS12355 (AWH44_11855) argD 2400787..2402007 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AWH44_RS12360 (AWH44_11860) yhfK 2402074..2404164 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AWH44_RS12365 (AWH44_11865) crp 2404215..2404847 (-) 633 WP_001698625.1 cAMP-activated global transcriptional regulator CRP Regulator
  AWH44_RS12375 (AWH44_11875) yhfA 2405149..2405553 (+) 405 WP_001148908.1 OsmC family protein -
  AWH44_RS12380 (AWH44_11880) prkB 2405608..2406477 (-) 870 WP_001274680.1 phosphoribulokinase -
  AWH44_RS12385 (AWH44_11885) yheU 2406531..2406749 (-) 219 WP_000907085.1 YheU family protein -
  AWH44_RS12390 (AWH44_11890) yheT 2406743..2407765 (-) 1023 WP_000057356.1 hydrolase -
  AWH44_RS12395 (AWH44_11895) yheS 2407765..2409678 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23652.48 Da        Isoelectric Point: 8.2710

>NTDB_id=143318 AWH44_RS12365 WP_001698625.1 2404215..2404847(-) (crp) [Escherichia coli strain HST04]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVISEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=143318 AWH44_RS12365 WP_001698625.1 2404215..2404847(-) (crp) [Escherichia coli strain HST04]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCATTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

77.451

97.143

0.752
  crp Acinetobacter baumannii D1279779

46.86

98.571

0.462