Detailed information NTG0141219

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MNA02_RS03205
• Genome accession: NZ_CP010999
• Coordinates: 593226..594227 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain MN-BM-A02
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 588226..599227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MNA02_RS03185 (MNA02_617)	smpB	589333..589797 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
MNA02_RS03190 (MNA02_618)	-	589951..591357 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
MNA02_RS03195 (MNA02_619)	-	591359..591724 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
MNA02_RS03200 (MNA02_620)	-	591827..592912 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
MNA02_RS03205 (MNA02_621)	ccpA	593226..594227 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
MNA02_RS10035 (MNA02_622)	-	594286..594483 (+)	198	WP_014608125.1	hypothetical protein	-
MNA02_RS11530	-	594589..594813 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
MNA02_RS03210 (MNA02_623)	-	594814..595353 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
MNA02_RS03215 (MNA02_625)	-	595366..596481 (+)	1116	WP_011680937.1	glycerate kinase	-
MNA02_RS03220 (MNA02_626)	-	596528..596983 (-)	456	WP_011680938.1	YueI family protein	-
MNA02_RS03225 (MNA02_627)	eno	597192..598496 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
MNA02_RS03230 (MNA02_628)	-	598648..598833 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=141219 MNA02_RS03205 WP_004197422.1 593226..594227(+) (ccpA) [Streptococcus thermophilus strain MN-BM-A02]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=141219 MNA02_RS03205 WP_004197422.1 593226..594227(+) (ccpA) [Streptococcus thermophilus strain MN-BM-A02]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547