Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   VAB027_RS12775 Genome accession   NZ_CP010812
Coordinates   2747610..2749778 (-) Length   722 a.a.
NCBI ID   WP_200894337.1    Uniprot ID   -
Organism   Vibrio cholerae strain 10432-62     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2742610..2754778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAB027_RS12755 (VAB027_2520) kdsB 2743888..2744661 (-) 774 WP_000011336.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  VAB027_RS12760 (VAB027_2521) - 2744661..2744840 (-) 180 WP_000350068.1 Trm112 family protein -
  VAB027_RS12765 (VAB027_2522) lpxK 2744821..2745828 (-) 1008 WP_046127363.1 tetraacyldisaccharide 4'-kinase -
  VAB027_RS12770 (VAB027_2523) msbA 2745831..2747579 (-) 1749 WP_000052155.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  VAB027_RS12775 (VAB027_2524) comEC 2747610..2749778 (-) 2169 WP_200894337.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  VAB027_RS12780 (VAB027_2525) - 2749862..2750392 (+) 531 WP_001881633.1 DUF2062 domain-containing protein -
  VAB027_RS12785 (VAB027_2526) lolE 2750507..2751751 (-) 1245 WP_046126887.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  VAB027_RS12790 (VAB027_2527) lolD 2751752..2752438 (-) 687 WP_001061290.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  VAB027_RS12795 (VAB027_2528) lolC 2752431..2753639 (-) 1209 WP_000468893.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  VAB027_RS12800 (VAB027_2529) - 2753815..2754390 (+) 576 WP_000999601.1 PilZ domain-containing protein -

Sequence

Protein


Download         Length: 722 a.a.        Molecular weight: 81605.23 Da        Isoelectric Point: 7.7631

>NTDB_id=139995 VAB027_RS12775 WP_200894337.1 2747610..2749778(-) (comEC) [Vibrio cholerae strain 10432-62]
MPSWGWAWLCLIVMVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGPDIIIKGRVDSFFTQTRYAYEGFVLI
HEVNGQTLNKMTRPRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYMAQSVVARAVVKPDTAYQIVQESGIR
SSLFFELEQLTHTSPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHIGIAFSVGYFFGLGMMRFHAQLLWSP
FVCGALLAVLYAWLAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLVAVLLWSPFASLSNSFWMSFLAVAIVLYQ
LASQSQRQVWWKALLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVIVPALFLGLLLMVVWPSVAAAYWPWV
DWTFFPLDWALQFADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMMGLWWWFPSLTPLWRMDVLDVGHGLAI
VIEQDERAIVYDTGSSWPGGSYVQSVIEPILQQRGLRQVDGVILSHLDNDHAGDWQGLAERWQPNWIRASQLGTEFMPCI
RGESWQWQSLHFTVLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEWLLARDGAQLQSEVMIVPHHGSKTSS
TAEFIAQVNPKLAIASVAKDNRWNLPNPQVVARYQAQQVEWLDTGHAGQISLFFYPDQLDWFTQRSLGWQPWYRQMLRKG
VE

Nucleotide


Download         Length: 2169 bp        

>NTDB_id=139995 VAB027_RS12775 WP_200894337.1 2747610..2749778(-) (comEC) [Vibrio cholerae strain 10432-62]
ATGCCGAGTTGGGGCTGGGCTTGGTTATGCCTTATTGTTATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCT
TGGCTTCGTGGCTGCCATACTAACCATTGTGCTACAGGGCAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAG
GGCCGGATATTATCATAAAAGGCCGTGTTGACAGCTTTTTTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATT
CATGAAGTGAATGGACAAACCTTAAACAAAATGACTCGCCCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAA
TGACCGCGTCGAATTTTCGGTAACTCTCAAGCCGATAGTAGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATT
ACATGGCGCAATCTGTCGTCGCACGAGCGGTCGTAAAACCTGACACCGCTTATCAAATTGTGCAAGAGAGTGGCATAAGG
TCAAGTTTGTTTTTTGAGCTGGAACAATTAACGCATACCAGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGA
GCGAAAAGGTATTGATGAGCAAGAGTGGCAAGCCTTACGCAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTGC
ACATTGGTATCGCTTTTAGCGTGGGTTATTTTTTCGGGCTCGGCATGATGCGTTTTCATGCTCAGTTATTGTGGTCCCCT
TTTGTGTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGGCTGGCCGGATTTACGTTGCCTACTCAGCGTGCATTGATTAT
GTGCTTACTCAATGTGGCGTTGATCATGTTGGCTTTTCCTCTTTCCGCGCTCAAGCGGATTCTACTCACCTTAGTCGCGG
TCTTGCTTTGGTCGCCATTCGCCTCACTTTCAAACAGTTTCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAA
TTAGCCAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCTCTGCTTTGGGCGCAGGTGTTTCTCGTCTGTTTAATGGCGCC
GGTCACGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGCAGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGG
TGATTGTCCCAGCTTTGTTTTTGGGTCTATTACTCATGGTGGTATGGCCCAGTGTGGCCGCCGCTTACTGGCCTTGGGTG
GATTGGACGTTTTTTCCGCTCGATTGGGCTTTGCAGTTTGCCGATGTAGGCTGGTGGGTGGTACCCAGCAAAGTACAAGG
TGTGGTCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCGATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGA
TGGGCTTATGGTGGTGGTTTCCCTCTCTCACTCCACTTTGGCGAATGGACGTGCTGGATGTTGGACATGGCTTGGCGATT
GTGATTGAGCAAGATGAGCGAGCAATTGTCTACGATACAGGCAGCAGTTGGCCGGGAGGCAGCTATGTGCAAAGCGTGAT
TGAGCCTATTCTCCAACAGCGAGGGCTACGCCAAGTCGATGGAGTGATTTTAAGTCATCTCGATAATGATCATGCGGGTG
ATTGGCAAGGTTTAGCTGAGCGCTGGCAACCCAATTGGATTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATC
CGTGGTGAAAGCTGGCAGTGGCAATCTCTCCATTTTACGGTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCA
GCATTCGTGTGTGATTCGTATGACCGATACTCAGTCTAACCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGG
AGTGGCTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTGAGGTGATGATCGTGCCGCATCACGGCAGTAAAACGTCGTCC
ACCGCAGAGTTTATTGCCCAAGTGAATCCCAAACTTGCGATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAA
TCCGCAAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGAGTGGCTAGATACTGGACACGCTGGGCAAATTAGCCTCTTTT
TCTATCCAGATCAGCTGGATTGGTTTACCCAGCGTAGCCTTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGA
GTAGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(183-439)

Domain of unknown function (DUF4131) (DUF4131)

(7-148)

Metallo-beta-lactamase superfamily (Lactamase_B)

(474-654)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

99.307

100

0.993
  comEC Vibrio parahaemolyticus RIMD 2210633

40.984

100

0.416
  comEC Vibrio campbellii strain DS40M4

40.715

100

0.41

Multiple sequence alignment