Detailed information    

insolico Bioinformatically predicted

Overview


Name   crp   Type   Regulator
Locus tag   VAB027_RS06400 Genome accession   NZ_CP010812
Coordinates   1375997..1376629 (-) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain 10432-62     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1352256..1392884 1375997..1376629 within 0


Gene organization within MGE regions


Location: 1352256..1392884
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAB027_RS06280 (VAB027_1232) - 1352256..1353557 (-) 1302 WP_235290684.1 McrC family protein -
  VAB027_RS06285 (VAB027_1233) - 1353564..1354703 (-) 1140 WP_046126404.1 AAA family ATPase -
  VAB027_RS06290 (VAB027_1234) - 1354693..1355289 (-) 597 WP_046126405.1 hypothetical protein -
  VAB027_RS06295 (VAB027_1235) - 1355282..1357513 (-) 2232 WP_046126406.1 Eco57I restriction-modification methylase domain-containing protein -
  VAB027_RS06300 (VAB027_1236) - 1357510..1358589 (-) 1080 WP_046126407.1 DNA adenine methylase -
  VAB027_RS06305 - 1358776..1359354 (+) 579 Protein_1223 IS3 family transposase -
  VAB027_RS19470 (VAB027_1238) - 1359392..1360615 (-) 1224 WP_080341744.1 site-specific integrase -
  VAB027_RS06315 (VAB027_1239) - 1360591..1360779 (-) 189 WP_000083581.1 hypothetical protein -
  VAB027_RS06320 (VAB027_1240) - 1360785..1361048 (-) 264 WP_001899820.1 hypothetical protein -
  VAB027_RS06325 (VAB027_1241) - 1361300..1362013 (-) 714 WP_000196481.1 S24 family peptidase -
  VAB027_RS06330 (VAB027_1242) - 1362089..1362283 (+) 195 WP_000844441.1 Cro/CI family transcriptional regulator -
  VAB027_RS20260 (VAB027_1243) - 1362571..1362735 (+) 165 WP_000532438.1 hypothetical protein -
  VAB027_RS06340 (VAB027_1244) - 1362904..1363872 (+) 969 WP_001905915.1 helix-turn-helix domain-containing protein -
  VAB027_RS06345 (VAB027_1245) - 1363936..1364754 (+) 819 WP_046126408.1 TIGR02642 family protein -
  VAB027_RS06350 (VAB027_1246) - 1364868..1365713 (+) 846 WP_080341745.1 hypothetical protein -
  VAB027_RS06355 (VAB027_1247) - 1365706..1367403 (+) 1698 WP_046126409.1 terminase -
  VAB027_RS06360 (VAB027_1248) - 1367400..1369487 (+) 2088 WP_044125582.1 hypothetical protein -
  VAB027_RS06365 (VAB027_1249) - 1369782..1369994 (+) 213 WP_000066470.1 cold-shock protein -
  VAB027_RS20265 (VAB027_1250) - 1370224..1370373 (+) 150 WP_000747118.1 hypothetical protein -
  VAB027_RS20470 - 1370507..1370665 (+) 159 Protein_1237 sodium:proton antiporter -
  VAB027_RS06370 (VAB027_1251) - 1370735..1371658 (-) 924 Protein_1238 IS5 family transposase -
  VAB027_RS06375 (VAB027_1252) - 1371999..1372553 (+) 555 WP_046126410.1 outer membrane beta-barrel protein -
  VAB027_RS06380 (VAB027_1253) uraH 1373312..1373695 (+) 384 WP_000779472.1 hydroxyisourate hydrolase -
  VAB027_RS06385 (VAB027_1254) - 1373708..1374211 (+) 504 WP_000700649.1 heme-binding protein -
  VAB027_RS06395 (VAB027_1255) - 1374612..1375934 (+) 1323 WP_046126018.1 IS4 family transposase -
  VAB027_RS06400 (VAB027_1256) crp 1375997..1376629 (-) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  VAB027_RS06405 (VAB027_1257) - 1376872..1377741 (-) 870 WP_001274667.1 phosphoribulokinase -
  VAB027_RS06410 (VAB027_1258) - 1377838..1378047 (-) 210 WP_001888622.1 YheU family protein -
  VAB027_RS06415 (VAB027_1259) - 1378176..1379165 (-) 990 WP_046126411.1 hydrolase -
  VAB027_RS06420 (VAB027_1260) - 1379162..1379647 (-) 486 WP_001278732.1 TIGR02444 family protein -
  VAB027_RS06425 (VAB027_1261) - 1379648..1381564 (-) 1917 WP_046126412.1 ABC transporter ATP-binding protein -
  VAB027_RS06430 (VAB027_1262) kefG 1381687..1382277 (+) 591 WP_001245312.1 glutathione-regulated potassium-efflux system ancillary protein KefG -
  VAB027_RS06435 (VAB027_1264) kefB 1382258..1384060 (+) 1803 WP_000188331.1 glutathione-regulated potassium-efflux system protein KefB -
  VAB027_RS06440 - 1384070..1384270 (+) 201 WP_000810609.1 YheV family putative zinc ribbon protein -
  VAB027_RS06445 (VAB027_1265) slyD 1384362..1384967 (+) 606 WP_000687664.1 peptidylprolyl isomerase -
  VAB027_RS06450 (VAB027_1266) - 1385131..1386111 (+) 981 WP_046126413.1 isoaspartyl peptidase/L-asparaginase family protein -
  VAB027_RS06455 (VAB027_1267) - 1386239..1387537 (+) 1299 WP_000527934.1 adenylosuccinate synthase -
  VAB027_RS06460 (VAB027_1268) motX 1387745..1388380 (+) 636 WP_001883957.1 flagellar protein MotX -
  VAB027_RS06465 (VAB027_1269) - 1388407..1390236 (-) 1830 WP_046126414.1 DUF3413 domain-containing protein -
  VAB027_RS06470 (VAB027_1270) rnr 1390419..1392884 (+) 2466 WP_046126415.1 ribonuclease R -

Sequence


Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=139986 VAB027_RS06400 WP_000242749.1 1375997..1376629(-) (crp) [Vibrio cholerae strain 10432-62]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=139986 VAB027_RS06400 WP_000242749.1 1375997..1376629(-) (crp) [Vibrio cholerae strain 10432-62]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAGTTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGATGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAAAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1

  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733

  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467


Multiple sequence alignment