Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HSISS4_RS06895 Genome accession   NZ_CP013216
Coordinates   1539457..1540101 (-) Length   214 a.a.
NCBI ID   WP_002884791.1    Uniprot ID   -
Organism   Streptococcus salivarius strain HSISS4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1534457..1545101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS06870 (HSISS4_01341) - 1536534..1537532 (-) 999 WP_021143822.1 NAD(P)/FAD-dependent oxidoreductase -
  HSISS4_RS06875 (HSISS4_01342) trmD 1537534..1538253 (-) 720 WP_002886864.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  HSISS4_RS06880 (HSISS4_01343) rimM 1538243..1538761 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  HSISS4_RS06895 (HSISS4_01344) vraR 1539457..1540101 (-) 645 WP_002884791.1 response regulator transcription factor Regulator
  HSISS4_RS06900 (HSISS4_01345) - 1540091..1541101 (-) 1011 WP_013990239.1 sensor histidine kinase -
  HSISS4_RS06905 (HSISS4_01346) liaF 1541098..1541796 (-) 699 WP_014634809.1 cell wall-active antibiotics response protein LiaF -
  HSISS4_RS06910 (HSISS4_01347) - 1541959..1542717 (-) 759 WP_014634810.1 potassium channel family protein -
  HSISS4_RS06915 (HSISS4_01348) stkP/pknB 1542865..1544739 (-) 1875 WP_021143821.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23977.31 Da        Isoelectric Point: 4.5814

>NTDB_id=139508 HSISS4_RS06895 WP_002884791.1 1539457..1540101(-) (vraR) [Streptococcus salivarius strain HSISS4]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAGNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=139508 HSISS4_RS06895 WP_002884791.1 1539457..1540101(-) (vraR) [Streptococcus salivarius strain HSISS4]
ATGTCGAATAAGATTAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGACTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTCGTTGGAGAGGCAGGGAATGGTCGAGAGGGTGTTGATCTTGCCTTGGAACTGCGACCAGATGTCG
TCGTTATGGACCTTGTTATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGAGCCAAAGGCTATATGCTTAA
AACCAGCAGTGCGGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCATGATAGCCATCCGGACCTACACGATGACTTGACGGCACGTGAACGTGATATCTTGGCCCTTTTG
GCTAAGGGGTATGACAATCAAACCATTGCTAATGAGCTATTTATTTCGTTGAAAACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTTGTTTATGCCTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment