Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AB847_RS21450 Genome accession   NZ_CP013031
Coordinates   4281312..4281944 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain H1827/12     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4276312..4286944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB847_RS21420 (AB847_21390) yheS 4276481..4278394 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AB847_RS21425 (AB847_21395) yheT 4278394..4279416 (+) 1023 WP_000057356.1 hydrolase -
  AB847_RS21430 (AB847_21400) yheU 4279410..4279628 (+) 219 WP_000907085.1 YheU family protein -
  AB847_RS21435 (AB847_21405) prkB 4279682..4280551 (+) 870 WP_001274680.1 phosphoribulokinase -
  AB847_RS21440 (AB847_21410) yhfA 4280606..4281010 (-) 405 WP_001148908.1 OsmC family protein -
  AB847_RS21450 (AB847_21420) crp 4281312..4281944 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AB847_RS21455 (AB847_21425) yhfK 4281995..4284085 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AB847_RS21460 (AB847_21430) argD 4284152..4285372 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AB847_RS21465 (AB847_21435) pabA 4285458..4286021 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AB847_RS21470 (AB847_21440) fic 4286053..4286655 (-) 603 WP_000502522.1 putative adenosine monophosphate-protein transferase Fic -
  AB847_RS21475 (AB847_21445) yhfG 4286645..4286812 (-) 168 WP_000736861.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=138560 AB847_RS21450 WP_000242755.1 4281312..4281944(+) (crp) [Escherichia coli strain H1827/12]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=138560 AB847_RS21450 WP_000242755.1 4281312..4281944(+) (crp) [Escherichia coli strain H1827/12]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGCCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment