Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AKK22_RS00850 Genome accession   NZ_CP013029
Coordinates   90242..90874 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2012C-4227     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 85242..95874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AKK22_RS00825 (AKK22_00370) yhfG 85375..85542 (+) 168 WP_000736863.1 YhfG family protein -
  AKK22_RS00830 (AKK22_00375) fic 85532..86134 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  AKK22_RS00835 (AKK22_00380) pabA 86166..86729 (+) 564 WP_000601849.1 aminodeoxychorismate synthase component 2 -
  AKK22_RS00840 (AKK22_00385) argD 86815..88035 (+) 1221 WP_032207219.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AKK22_RS00845 (AKK22_00390) yhfK 88101..90191 (-) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  AKK22_RS00850 (AKK22_00395) crp 90242..90874 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AKK22_RS00860 (AKK22_00405) yhfA 91176..91580 (+) 405 WP_001148908.1 OsmC family protein -
  AKK22_RS00865 (AKK22_00410) prkB 91635..92504 (-) 870 WP_001274680.1 phosphoribulokinase -
  AKK22_RS00870 (AKK22_00415) yheU 92558..92776 (-) 219 WP_000907085.1 YheU family protein -
  AKK22_RS00875 (AKK22_00420) yheT 92770..93792 (-) 1023 WP_000057379.1 hydrolase -
  AKK22_RS00880 (AKK22_00425) yheS 93792..95705 (-) 1914 WP_032207216.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=138414 AKK22_RS00850 WP_000242755.1 90242..90874(-) (crp) [Escherichia coli strain 2012C-4227]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=138414 AKK22_RS00850 WP_000242755.1 90242..90874(-) (crp) [Escherichia coli strain 2012C-4227]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467