Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MJ49_RS14260 Genome accession   NZ_CP013025
Coordinates   2707897..2708529 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2009C-3133     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2702897..2713529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ49_RS14235 (MJ49_13495) yhfG 2703029..2703196 (+) 168 WP_000736860.1 YhfG family protein -
  MJ49_RS14240 (MJ49_13500) fic 2703186..2703788 (+) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  MJ49_RS14245 (MJ49_13505) pabA 2703820..2704383 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  MJ49_RS14250 (MJ49_13510) argD 2704469..2705689 (+) 1221 WP_000963795.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MJ49_RS14255 (MJ49_13515) yhfK 2705756..2707846 (-) 2091 WP_001318073.1 YccS/YhfK family putative transporter -
  MJ49_RS14260 (MJ49_13520) crp 2707897..2708529 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MJ49_RS14270 (MJ49_13530) yhfA 2708831..2709235 (+) 405 WP_001148908.1 OsmC family protein -
  MJ49_RS14275 (MJ49_13535) prkB 2709290..2710159 (-) 870 WP_001274680.1 phosphoribulokinase -
  MJ49_RS14280 (MJ49_13540) yheU 2710213..2710431 (-) 219 WP_000907085.1 YheU family protein -
  MJ49_RS14285 (MJ49_13545) yheT 2710425..2711447 (-) 1023 WP_000057375.1 hydrolase -
  MJ49_RS14290 (MJ49_13550) yheS 2711447..2713360 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=138374 MJ49_RS14260 WP_000242755.1 2707897..2708529(-) (crp) [Escherichia coli strain 2009C-3133]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=138374 MJ49_RS14260 WP_000242755.1 2707897..2708529(-) (crp) [Escherichia coli strain 2009C-3133]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment