Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   SAST43_RS08430 Genome accession   NZ_CP012974
Coordinates   1731132..1732121 (-) Length   329 a.a.
NCBI ID   WP_000219066.1    Uniprot ID   P67655
Organism   Staphylococcus aureus strain ST20130943     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1726132..1737121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAST43_RS08415 (SAST43_01678) acsA 1727333..1729039 (-) 1707 WP_000862095.1 acetate--CoA ligase -
  SAST43_RS08420 (SAST43_01679) - 1729208..1729840 (+) 633 WP_001015995.1 hypothetical protein -
  SAST43_RS08425 (SAST43_03933) - 1729865..1731034 (+) 1170 WP_001184006.1 acetoin utilization protein AcuC -
  SAST43_RS08430 (SAST43_01681) ccpA 1731132..1732121 (-) 990 WP_000219066.1 catabolite control protein A Regulator
  SAST43_RS08435 - 1732194..1732307 (-) 114 WP_001803513.1 hypothetical protein -
  SAST43_RS08440 (SAST43_01682) - 1732661..1733752 (-) 1092 WP_000066384.1 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase -
  SAST43_RS08445 - 1734208..1734291 (-) 84 WP_031797498.1 hypothetical protein -
  SAST43_RS08450 (SAST43_03934) - 1734447..1735800 (-) 1354 Protein_1622 hypothetical protein -
  SAST43_RS08455 (SAST43_01685) - 1735874..1736365 (-) 492 WP_000383813.1 DUF948 domain-containing protein -

Sequence

Protein


Download         Length: 329 a.a.        Molecular weight: 36060.24 Da        Isoelectric Point: 5.5054

>NTDB_id=138013 SAST43_RS08430 WP_000219066.1 1731132..1732121(-) (ccpA) [Staphylococcus aureus strain ST20130943]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide


Download         Length: 990 bp        

>NTDB_id=138013 SAST43_RS08430 WP_000219066.1 1731132..1732121(-) (ccpA) [Staphylococcus aureus strain ST20130943]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAAGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATTAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAATGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(4-49)

Periplasmic binding protein-like domain (Peripla_BP_3)

(171-328)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P67655

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

47.879

100

0.48
  ccpA Streptococcus gordonii str. Challis substr. CH1

47.112

100

0.471
  ccpA Streptococcus pneumoniae D39

46.201

100

0.462

Multiple sequence alignment