Detailed information NTG0136895

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: SB24_RS12370
• Genome accession: NZ_CP010406
• Coordinates: 2585126..2586289 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. Pc3
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2580126..2591289

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SB24_RS12350 (SB24_12350)	-	2580500..2581696 (+)	1197	WP_039253634.1	glycosyltransferase	-
SB24_RS12355 (SB24_12355)	-	2581829..2582905 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
SB24_RS12360 (SB24_12360)	-	2582995..2584251 (-)	1257	WP_039253637.1	LCP family protein	-
SB24_RS12365 (SB24_12365)	-	2584256..2584903 (-)	648	WP_003151384.1	YigZ family protein	-
SB24_RS12370 (SB24_12370)	degS	2585126..2586289 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
SB24_RS12375 (SB24_12375)	degU	2586366..2587055 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
SB24_RS12380 (SB24_12380)	-	2587153..2588001 (+)	849	WP_015418336.1	DegV family protein	-
SB24_RS12385 (SB24_12385)	comFA	2588109..2589494 (+)	1386	WP_039253641.1	DEAD/DEAH box helicase	Machinery gene
SB24_RS12390 (SB24_12390)	-	2589552..2589836 (+)	285	WP_039253645.1	competence protein ComFB	-
SB24_RS12395 (SB24_12395)	comFC	2589842..2590531 (+)	690	WP_197061611.1	phosphoribosyltransferase family protein	Machinery gene
SB24_RS12400 (SB24_12400)	-	2590605..2591024 (+)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=136895 SB24_RS12370 WP_007407484.1 2585126..2586289(+) (degS) [Bacillus sp. Pc3]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=136895 SB24_RS12370 WP_007407484.1 2585126..2586289(+) (degS) [Bacillus sp. Pc3]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951