Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SanJ4211_RS02210 Genome accession   NZ_CP012805
Coordinates   425762..426394 (+) Length   210 a.a.
NCBI ID   WP_021001361.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4211     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 420762..431394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS02190 (SanJ4211_0408) - 421198..421938 (+) 741 WP_003025814.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SanJ4211_RS02195 (SanJ4211_0409) stkP 421935..423809 (+) 1875 WP_021001359.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SanJ4211_RS02200 (SanJ4211_0410) liaF 424070..424768 (+) 699 WP_003025810.1 cell wall-active antibiotics response protein LiaF -
  SanJ4211_RS02205 (SanJ4211_0411) - 424765..425760 (+) 996 WP_021001360.1 sensor histidine kinase -
  SanJ4211_RS02210 (SanJ4211_0412) vraR 425762..426394 (+) 633 WP_021001361.1 response regulator transcription factor Regulator
  SanJ4211_RS02215 (SanJ4211_0413) - 426434..427834 (+) 1401 WP_057489579.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SanJ4211_RS02220 (SanJ4211_0414) - 427836..428210 (+) 375 WP_021001363.1 S1 RNA-binding domain-containing protein -
  SanJ4211_RS02225 (SanJ4211_0415c) - 428336..428653 (-) 318 WP_041784094.1 DUF960 domain-containing protein -
  SanJ4211_RS02230 (SanJ4211_0416c) - 428773..429306 (-) 534 WP_003025799.1 DUF402 domain-containing protein -
  SanJ4211_RS02235 (SanJ4211_0417c) recX 429393..430169 (-) 777 WP_003025796.1 recombination regulator RecX Regulator
  SanJ4211_RS02240 (SanJ4211_0418c) - 430232..431008 (-) 777 WP_003025794.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23699.25 Da        Isoelectric Point: 4.7341

>NTDB_id=136495 SanJ4211_RS02210 WP_021001361.1 425762..426394(+) (vraR) [Streptococcus anginosus strain J4211]
MHILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVEKALELRPDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=136495 SanJ4211_RS02210 WP_021001361.1 425762..426394(+) (vraR) [Streptococcus anginosus strain J4211]
ATGCATATTTTATTAGTAGATGACCATGAAATGGTACGACTTGGCTTGAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAAAGCTTTGGAGTTGCGCCCGGATGTGATTATGATGGACA
TTGTTATGCCTGAAATGAGTGGGATTGAAGCGACACTTGCTATTTTGAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGACGCAGGTGCTAAAGGATATATGCTGAAAACATCTAGTGC
TGATGATATTTTACGAGCTGTCCGAAAAGTAGCTAAGGGTGAACTTGCCATTGAAACAGAGGTCAGCCAAAAAGTGGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

98.095

0.533
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414