Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AO055_RS21130 Genome accession   NZ_CP012802
Coordinates   4078403..4079035 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O157:H7 strain WS4202     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4073403..4084035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AO055_RS21100 (AO055_21075) yheS 4073572..4075485 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AO055_RS21105 (AO055_21080) yheT 4075485..4076507 (+) 1023 WP_000057377.1 hydrolase -
  AO055_RS21110 (AO055_21085) yheU 4076501..4076719 (+) 219 WP_000907085.1 YheU family protein -
  AO055_RS21115 (AO055_21090) prkB 4076773..4077642 (+) 870 WP_001274677.1 phosphoribulokinase -
  AO055_RS21120 (AO055_21095) yhfA 4077697..4078101 (-) 405 WP_001148908.1 OsmC family protein -
  AO055_RS21130 (AO055_21105) crp 4078403..4079035 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AO055_RS21135 (AO055_21110) yhfK 4079086..4081176 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AO055_RS21140 (AO055_21115) argD 4081243..4082463 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AO055_RS21145 (AO055_21120) pabA 4082549..4083112 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  AO055_RS21150 (AO055_21125) fic 4083144..4083746 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  AO055_RS21155 (AO055_21130) yhfG 4083736..4083903 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=136434 AO055_RS21130 WP_000242755.1 4078403..4079035(+) (crp) [Escherichia coli O157:H7 strain WS4202]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=136434 AO055_RS21130 WP_000242755.1 4078403..4079035(+) (crp) [Escherichia coli O157:H7 strain WS4202]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467