Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ACH32_RS11150 Genome accession   NZ_CP012756
Coordinates   2200220..2202205 (+) Length   661 a.a.
NCBI ID   WP_000229256.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JS395     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2195220..2207205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH32_RS11120 (ACH32_11115) - 2196261..2196354 (+) 94 Protein_2137 hypothetical protein -
  ACH32_RS11125 (ACH32_11120) prfB 2196534..2197644 (+) 1111 WP_100205847.1 peptide chain release factor 2 -
  ACH32_RS11135 (ACH32_11130) - 2198055..2198894 (+) 840 WP_000749393.1 CHAP domain-containing protein -
  ACH32_RS11140 (ACH32_11135) - 2199068..2199718 (+) 651 WP_000538142.1 YfbR-like 5'-deoxynucleotidase -
  ACH32_RS11145 (ACH32_11140) - 2199715..2199951 (+) 237 WP_000638419.1 CsbA family protein -
  ACH32_RS11150 (ACH32_11145) uvrB 2200220..2202205 (+) 1986 WP_000229256.1 excinuclease ABC subunit UvrB Machinery gene
  ACH32_RS11155 (ACH32_11150) uvrA 2202213..2205041 (+) 2829 WP_000662699.1 excinuclease ABC subunit UvrA Machinery gene
  ACH32_RS11160 (ACH32_11155) hprK 2205418..2206350 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -
  ACH32_RS11165 (ACH32_11160) lgt 2206356..2207195 (+) 840 WP_000513299.1 prolipoprotein diacylglyceryl transferase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76708.41 Da        Isoelectric Point: 5.0538

>NTDB_id=136357 ACH32_RS11150 WP_000229256.1 2200220..2202205(+) (uvrB) [Staphylococcus aureus strain JS395]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKMKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRIERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDRGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=136357 ACH32_RS11150 WP_000229256.1 2200220..2202205(+) (uvrB) [Staphylococcus aureus strain JS395]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCAGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGAGACGTCGTTGAAATATTCCCAGCCTCTAAGGAAGAACTATGTA
TACGAGTTGAGTTTTTTGGTGACGAAATCGATCGTATCCGAGAAGTTAATTATTTAACAGGTGAAGTGTTGAAAGAAAGG
GAACATTTTGCAATCTTCCCTGCATCTCACTTCGTCACACGTGAAGAAAAGATGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAATT
ATGATTTAGAAATGATGCGTGAGATGGGGTTCTGTTCAGGAATTGAAAACTATTCTGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGATTTAGATTACCGAGTGCGT
TAGATAACCGCCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTTTATGTATCTGCAACGCCTGGTCCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATACAAACAAGGATTGAGCGTAATGAACGCGTACTTGTTACAA
CACTTACTAAAAAGATGAGCGAAGATTTAACCACATACATGAAAGAAGCAGGCATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATTGAAATTATAAGAGATTTACGTATGGGTACGTATGATGTCATTGTAGGGATTAATTTATT
AAGAGAGGGTATTGATATTCCAGAAGTGTCTTTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCAAATC
GTTCATTAATACAAACAATAGGTAGAGCCGCACGTAATGATCGAGGCGAAGTGATTATGTATGCTGATAAAATGACTGAT
TCAATGAAGTATGCTATTGATGAAACGCAACGTCGTCGAGAAATTCAAATGAAACACAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(14-140)

Ultra-violet resistance protein B (UvrB)

(553-594)

Helicase conserved C-terminal domain (Helicase_C)

(435-546)

UvrB/uvrC motif (UVR)

(626-659)

UvrB interaction domain (UvrB_inter)

(161-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae D39

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae TIGR4

67.534

98.79

0.667

Multiple sequence alignment