Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   SanJ4206_RS04060 Genome accession   NZ_CP012719
Coordinates   831912..833900 (+) Length   662 a.a.
NCBI ID   WP_003027986.1    Uniprot ID   A0ABD7NE21
Organism   Streptococcus anginosus strain J4206     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 826912..838900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS04045 (SanJ4206_0765c) - 827775..828515 (-) 741 WP_003024883.1 amino acid ABC transporter ATP-binding protein -
  SanJ4206_RS04050 (SanJ4206_0766c) - 828515..830698 (-) 2184 WP_003027984.1 ABC transporter substrate-binding protein/permease -
  SanJ4206_RS04055 (SanJ4206_0767) - 830862..831821 (+) 960 WP_003027985.1 CPBP family intramembrane glutamic endopeptidase -
  SanJ4206_RS04060 (SanJ4206_0768) uvrB 831912..833900 (+) 1989 WP_003027986.1 excinuclease ABC subunit UvrB Machinery gene
  SanJ4206_RS04065 (SanJ4206_0769) - 833917..834480 (+) 564 WP_003027987.1 hypothetical protein -
  SanJ4206_RS04070 (SanJ4206_0770) - 834506..835051 (+) 546 WP_003027988.1 DUF1697 domain-containing protein -
  SanJ4206_RS04075 (SanJ4206_0771) pptA 835181..835924 (+) 744 WP_003027989.1 ABC transporter ATP-binding protein Regulator
  SanJ4206_RS04080 (SanJ4206_0772) - 835914..837554 (+) 1641 WP_003027990.1 hypothetical protein -
  SanJ4206_RS04085 (SanJ4206_0773) hemW 837680..838810 (+) 1131 WP_003027991.1 radical SAM family heme chaperone HemW -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75637.65 Da        Isoelectric Point: 4.5177

>NTDB_id=136064 SanJ4206_RS04060 WP_003027986.1 831912..833900(+) (uvrB) [Streptococcus anginosus strain J4206]
MINRITDNKFKLVSKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFMTNDENMEIAIGKIQAELEEQLAFFEKEGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMVDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEREQTDTVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
ITDSMQKAMDETARRRQIQMAYNEEHGIVPQTIQKEIRDLISVTKSALPDKGEVVDIESLNKQERKDMIKKLEGQMQEAA
GLLDFELAAQIRDMILEIKAMD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=136064 SanJ4206_RS04060 WP_003027986.1 831912..833900(+) (uvrB) [Streptococcus anginosus strain J4206]
ATGATAAATAGAATTACGGACAATAAATTTAAACTGGTTTCTAAGTATGAGCCCTCAGGAGATCAACCACAGGCGATTGA
GCAATTAGTGGATAATATAGAGGGTGGTGAGAAAGCTCAGATTCTCATGGGAGCGACAGGAACTGGGAAGACCTATACTA
TGAGTCAGGTTATTCAAAAGGTTAATAAACCGACCTTAGTCATCGCTCATAATAAAACTCTGGCAGGTCAGCTTTATGGG
GAATTTAAGGAATTTTTCCCTGACAATGCGGTCGAATACTTTGTGTCTTACTATGATTACTATCAACCGGAAGCCTATGT
GCCTTCCAGTGATACCTATATTGAGAAGGACAGCTCTGTCAATGATGAGATTGACAAGCTTCGTCACTCAGCAACTTCGG
CTCTCTTGGAACGCAACGATGTGATTGTAGTGGCGTCAGTCAGCTGCATTTATGGTTTGGGTTCGCCTAAGGAATACTCC
GATAGCGTTGTCAGTCTGCGGCCGGGTTTAGAGATTTCACGGGATAAACTTCTCAATGATTTGGTGGATATCCAGTTTGA
GCGTAATGATATTGATTTTCAGCGGGGGAAATTCCGGGTGCGTGGTGATGTAGTAGAAATTTTTCCGGCTTCTCGTGATG
AGCATGCTTTTCGAGTAGAGTTTTTTGGTGATGAAATTGACCGTATTCGAGAAGTAGAAGCGTTGACGGGACAAGTTTTG
GGTGAAGTGGATCATTTAGCAATTTTCCCAGCTACTCACTTTATGACAAATGACGAAAATATGGAGATTGCTATTGGCAA
GATTCAAGCGGAATTAGAAGAACAACTAGCCTTTTTTGAAAAGGAAGGGAAACTTTTAGAAGCTCAGCGGCTGAAACAAA
GAACTGACTATGATATTGAAATGCTGCGCGAAATGGGCTACACGAATGGCGTAGAGAATTATTCTCGCCATATGGACGGA
CGGAGCGAAGGTGAGCCACCTTACACTTTACTAGATTTCTTCCCTGATGATTTTTTAATCATGGTGGACGAAAGTCATAT
GACGATGGGGCAAATCAAGGGTATGTATAATGGTGACCGCTCACGGAAGGAAATGTTGGTTAATTATGGATTTCGCTTGC
CTTCTGCCTTGGATAACCGCCCGCTGCGTCGGGAAGAATTTGAAAGTCATGTGCACCAGATTGTCTATGTATCTGCGACA
CCGGGCGACTATGAGCGGGAGCAGACGGATACAGTGATTGAGCAGATTATTCGACCAACTGGTCTGCTGGATCCAGAAGT
CGAAGTGCGTCCGACTATGGGTCAAATAGATGATCTTTTAGGCGAAATCAATGCGCGTGTTGAAAAGAATGAGCGGACCT
TTATCACAACGTTGACTAAAAAGATGGCAGAAGATCTGACGGATTACTTTAAAGAAATGGGAGTTAAGGTCAAATACATG
CACTCAGATATCAAGACCTTAGAGCGGACAGAAATTATCCGCGACCTGCGGTTAGGTGTCTTTGATGTTTTAGTCGGAAT
TAACCTGTTGCGTGAGGGAATTGATGTGCCAGAGGTTAGTCTGGTTGCCATTCTTGATGCAGACAAGGAAGGTTTCTTAC
GTAATGAGCGTGGTTTGATCCAAACCATTGGTCGGGCTGCCCGTAATAGTGAAGGCCACGTCATCATGTATGCTGACACA
ATCACAGATTCCATGCAAAAAGCTATGGATGAAACTGCCCGCCGTCGTCAGATTCAAATGGCTTATAACGAAGAACATGG
TATTGTACCGCAAACAATCCAGAAAGAAATCCGTGACCTAATCAGTGTGACAAAATCTGCTCTACCAGACAAGGGAGAAG
TGGTAGATATTGAAAGTCTTAACAAGCAGGAACGTAAAGATATGATTAAGAAACTAGAGGGACAAATGCAAGAAGCTGCC
GGACTTCTGGACTTCGAACTGGCGGCACAGATTCGGGATATGATTTTAGAGATAAAGGCGATGGATTGA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB/uvrC motif (UVR)

(626-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0ABD7NE21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

93.202

100

0.932
  uvrB Streptococcus pneumoniae D39

93.202

100

0.932
  uvrB Streptococcus pneumoniae TIGR4

93.051

100

0.931

Multiple sequence alignment