Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   RN80_RS00680 Genome accession   NZ_CP012646
Coordinates   123350..124261 (-) Length   303 a.a.
NCBI ID   WP_060627175.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 118350..129261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS00655 (RN80_00660) rsmA 118553..119425 (-) 873 WP_060627174.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  RN80_RS00660 (RN80_00665) - 119556..119864 (-) 309 WP_000333261.1 hypothetical protein -
  RN80_RS00665 (RN80_00670) - 119857..120498 (-) 642 WP_000565528.1 ABC transporter ATP-binding protein -
  RN80_RS00670 (RN80_00675) - 120500..122530 (-) 2031 WP_000825283.1 bacteriocin-associated integral membrane family protein -
  RN80_RS00675 (RN80_00680) - 122607..122903 (-) 297 WP_000815396.1 lactococcin 972 family bacteriocin -
  RN80_RS00680 (RN80_00685) comR 123350..124261 (-) 912 WP_060627175.1 helix-turn-helix domain-containing protein Regulator
  RN80_RS00685 (RN80_00690) rnmV 124333..124893 (-) 561 WP_060627176.1 ribonuclease M5 -
  RN80_RS00690 (RN80_00695) - 124893..125666 (-) 774 WP_060627177.1 TatD family hydrolase -
  RN80_RS00695 (RN80_00700) - 125824..127668 (+) 1845 WP_060627178.1 APC family permease -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35549.87 Da        Isoelectric Point: 4.4987

>NTDB_id=135309 RN80_RS00680 WP_060627175.1 123350..124261(-) (comR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPAYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIEDLFYEQLPNEEKIWFEATRATIDVIRSGRPEYGETVLDDYFKIIYDKELFLINELEV
INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACLDNLSSYDSLEAYIFSLNHIMEK
TQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSKLFADIIENSYLVTMLEKQWQEDLKKYL

Nucleotide


Download         Length: 912 bp        

>NTDB_id=135309 RN80_RS00680 WP_060627175.1 123350..124261(-) (comR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGTTAGGAGTTCCAGCTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAGGAAGCGTGTTTGGAAGAGATAGAGGATTTATTTTA
TGAGCAACTTCCTAATGAGGAAAAAATATGGTTTGAAGCTACTAGAGCAACGATAGATGTTATTCGAAGCGGACGACCAG
AATATGGGGAAACCGTACTGGACGATTATTTTAAAATAATTTATGATAAGGAATTGTTTTTGATAAATGAATTAGAAGTT
ATCAACTTATATTTTGCTATAGTGCTTACAAAGATAAAACAAGGTCAAAATCAGATTGAAGAAATTAACAGAATTCATTC
GTTTTTAGTTCGTTTGACAAATCATGTAGAATTAATTGCACCAGAATATCTGTTTGCTTTAAGTAACACTTTGTTTTCGG
GTCTAGCCTGTTTGGATAATTTGTCGTCTTATGATTCACTCGAAGCTTATATCTTTAGCCTTAATCATATAATGGAAAAA
ACACAAGATTTTCAGAAGAAACCAATTATATTAATGTTGGAGTGGAAATTATCTCTAATAATAAACAATGATTATGTTTC
TGCCGAACAGTTCTATCAGAAATCGAAGCTATTTGCTGATATAATAGAAAATTCTTATTTAGTTACTATGTTGGAGAAAC
AATGGCAAGAAGATTTAAAAAAATATTTATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(70-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

39.189

97.69

0.383
  comR Streptococcus pyogenes MGAS8232

37.829

100

0.38
  comR Streptococcus suis P1/7

37.966

97.36

0.37
  comR Streptococcus suis 05ZYH33

37.966

97.36

0.37