Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   DE8669_RS10665 Genome accession   NZ_CP012391
Coordinates   2088510..2088959 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   Q9JXJ2
Organism   Neisseria meningitidis strain DE8669     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2083510..2093959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8669_RS10635 (DE8669_2003) - 2084922..2085752 (+) 831 WP_033908430.1 DNA-methyltransferase -
  DE8669_RS10640 (DE8669_2004) - 2085809..2086408 (-) 600 WP_002219927.1 ScaI family restriction endonuclease -
  DE8669_RS13235 - 2086410..2086625 (-) 216 WP_025458585.1 helix-turn-helix domain-containing protein -
  DE8669_RS10650 (DE8669_2005) - 2087057..2087524 (-) 468 Protein_2023 transposase -
  DE8669_RS10655 (DE8669_2006) - 2087756..2087968 (+) 213 WP_002224145.1 SWIM zinc finger domain-containing protein -
  DE8669_RS15310 - 2088152..2088420 (+) 269 Protein_2025 5'-nucleotidase -
  DE8669_RS10665 (DE8669_2007) comP 2088510..2088959 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene
  DE8669_RS14550 comE 2089047..2089511 (-) 465 WP_162051247.1 ComEA family DNA-binding protein Machinery gene

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=133389 DE8669_RS10665 WP_002214937.1 2088510..2088959(-) (comP) [Neisseria meningitidis strain DE8669]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=133389 DE8669_RS10665 WP_002214937.1 2088510..2088959(-) (comP) [Neisseria meningitidis strain DE8669]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterProScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9JXJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49

Multiple sequence alignment