Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AKN41_RS19900 Genome accession   NZ_CP012376
Coordinates   4064000..4064590 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain GE3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4059000..4069590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AKN41_RS19885 (AKN41_3996) uhpT 4059640..4061031 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  AKN41_RS19890 (AKN41_3997) uhpC 4061169..4062488 (-) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  AKN41_RS19895 (AKN41_3998) uhpB 4062498..4064000 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  AKN41_RS19900 (AKN41_3999) letA 4064000..4064590 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  AKN41_RS19905 (AKN41_4000) ilvN 4064665..4064955 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  AKN41_RS19910 (AKN41_4001) ilvB 4064959..4066647 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  AKN41_RS19915 ivbL 4066753..4066851 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  AKN41_RS19920 tisB 4067416..4067505 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  AKN41_RS24980 ysdE 4067768..4067842 (-) 75 WP_211180519.1 protein YsdE -
  AKN41_RS19925 (AKN41_4003) emrD 4067924..4069108 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=133141 AKN41_RS19900 WP_000633668.1 4064000..4064590(-) (letA) [Escherichia coli strain GE3]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=133141 AKN41_RS19900 WP_000633668.1 4064000..4064590(-) (letA) [Escherichia coli strain GE3]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment