Detailed information NTG0132366

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: OB04_RS18120
• Genome accession: NZ_CP009796
• Coordinates: 3497903..3499060 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain SG6
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3492903..3504060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OB04_RS18090 (OB04_03554)	yvyF	3493157..3493576 (-)	420	WP_038429728.1	TIGR03826 family flagellar region protein	-
OB04_RS18095 (OB04_03555)	comFC	3493649..3494371 (-)	723	WP_038429729.1	comF operon protein ComFC	Machinery gene
OB04_RS18100 (OB04_03556)	comFB	3494335..3494631 (-)	297	WP_015483764.1	late competence protein ComFB	-
OB04_RS18105 (OB04_03557)	comFA	3494691..3496082 (-)	1392	WP_038429730.1	ATP-dependent helicase ComFA	Machinery gene
OB04_RS18110 (OB04_03558)	fakBA	3496188..3497033 (-)	846	WP_038429731.1	DegV family protein	-
OB04_RS18115 (OB04_03559)	degU	3497131..3497820 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
OB04_RS18120 (OB04_03560)	degS	3497903..3499060 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
OB04_RS18125 (OB04_03561)	yvyE	3499277..3499930 (+)	654	WP_003227979.1	YigZ family protein	-
OB04_RS18130 (OB04_03562)	tagV	3499930..3501105 (+)	1176	WP_038429732.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
OB04_RS18135 (OB04_03563)	tagO	3501178..3502254 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
OB04_RS18140 (OB04_03564)	tuaH	3502399..3503592 (-)	1194	WP_082201021.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=132366 OB04_RS18120 WP_003227983.1 3497903..3499060(-) (degS) [Bacillus subtilis strain SG6]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=132366 OB04_RS18120 WP_003227983.1 3497903..3499060(-) (degS) [Bacillus subtilis strain SG6]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1