Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   HKU488_RS09420 Genome accession   NZ_CP012045
Coordinates   1874024..1874620 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain HKU488     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1869024..1879620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKU488_RS09385 (HKU488_01775) - 1869085..1869390 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  HKU488_RS09390 (HKU488_01776) ruvX 1869402..1869821 (-) 420 WP_010922752.1 Holliday junction resolvase RuvX -
  HKU488_RS09395 (HKU488_01777) - 1869818..1870087 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  HKU488_RS09400 (HKU488_01778) spx 1870200..1870598 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  HKU488_RS09405 (HKU488_01779) recA 1870889..1872025 (-) 1137 WP_010922753.1 recombinase RecA Machinery gene
  HKU488_RS09410 (HKU488_01780) cinA 1872114..1873385 (-) 1272 WP_010922754.1 competence/damage-inducible protein A Machinery gene
  HKU488_RS09415 (HKU488_01781) - 1873454..1874014 (-) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  HKU488_RS09420 (HKU488_01782) ruvA 1874024..1874620 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  HKU488_RS09425 (HKU488_01783) - 1874622..1875842 (-) 1221 WP_010922756.1 MDR family MFS transporter -
  HKU488_RS09430 (HKU488_01784) hexB 1875853..1877835 (-) 1983 WP_010922757.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=131064 HKU488_RS09420 WP_002992186.1 1874024..1874620(-) (ruvA) [Streptococcus pyogenes strain HKU488]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=131064 HKU488_RS09420 WP_002992186.1 1874024..1874620(-) (ruvA) [Streptococcus pyogenes strain HKU488]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment