Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EP23_RS17705 Genome accession   NZ_CP009623
Coordinates   1107216..1107845 (-) Length   209 a.a.
NCBI ID   WP_037566926.1    Uniprot ID   -
Organism   Staphylococcus agnetis strain 908     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1102216..1112845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP23_RS17670 (EP23_05555) - 1102292..1102810 (-) 519 WP_060551423.1 acyl-CoA thioesterase -
  EP23_RS17675 (EP23_05560) - 1102823..1104058 (-) 1236 WP_060551424.1 aminopeptidase -
  EP23_RS17680 (EP23_05565) - 1104075..1104284 (-) 210 WP_060551425.1 DUF1128 domain-containing protein -
  EP23_RS17685 (EP23_05570) - 1104417..1104875 (+) 459 WP_060551426.1 low molecular weight protein-tyrosine-phosphatase -
  EP23_RS17690 (EP23_05575) - 1104883..1105158 (+) 276 WP_037566921.1 hypothetical protein -
  EP23_RS17695 (EP23_05580) - 1105274..1106545 (+) 1272 WP_060551427.1 YihY/virulence factor BrkB family protein -
  EP23_RS17700 (EP23_05585) - 1106581..1107150 (+) 570 WP_060551428.1 beta-class carbonic anhydrase -
  EP23_RS17705 (EP23_05590) vraR 1107216..1107845 (-) 630 WP_037566926.1 response regulator transcription factor Regulator
  EP23_RS17710 (EP23_05595) vraS 1107835..1108878 (-) 1044 WP_037566929.1 sensor histidine kinase Regulator
  EP23_RS17715 (EP23_05600) liaF 1108875..1109576 (-) 702 WP_060551429.1 cell wall-active antibiotics response protein LiaF -
  EP23_RS17720 (EP23_05605) - 1109589..1109975 (-) 387 WP_086375153.1 hypothetical protein -
  EP23_RS17725 (EP23_05610) map 1110074..1110832 (-) 759 WP_060551430.1 type I methionyl aminopeptidase -
  EP23_RS17730 (EP23_05615) - 1111061..1111378 (+) 318 WP_246864159.1 YkvA family protein -
  EP23_RS17735 (EP23_05620) - 1111498..1112529 (+) 1032 WP_060551432.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.31 Da        Isoelectric Point: 5.1805

>NTDB_id=130833 EP23_RS17705 WP_037566926.1 1107216..1107845(-) (vraR) [Staphylococcus agnetis strain 908]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAISKAHELKPDLILMDLVMTDMDGVEATTQIKKELPRIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSAKDIAEAIRKTFQGESVFEAEVLVKMRNRMRQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=130833 EP23_RS17705 WP_037566926.1 1107216..1107845(-) (vraR) [Staphylococcus agnetis strain 908]
ATGACAATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGAATTTCGAGTTATCTTTCTACACAACCAGA
CATTGAAGTAGTAGGTGAAGGGGCGTCAGGTAAAGAGGCAATCTCAAAAGCACATGAACTGAAACCGGATTTAATTTTAA
TGGATTTAGTGATGACAGATATGGATGGGGTTGAGGCTACGACACAAATTAAAAAAGAGTTACCACGTATCAAAGTGGTG
ATGCTTACAAGTTACATTGAGGATAAAGAAGTTTATCGCGCTTTAGATGCCGGTGTCGACAGCTATATTTTAAAAACAAC
AAGTGCAAAAGATATTGCCGAAGCTATTCGTAAAACATTCCAAGGTGAATCTGTTTTTGAAGCAGAAGTATTAGTGAAAA
TGCGAAATCGTATGCGACAAAGAGCTGAACTTTACGAATTGTTAACGGAACGTGAAATGGAAATTTTATTGCTGATTTCC
AAAGGGTATTCGAATCAAGAAATTGCGAGCGCTTCACATATTACGATTAAGACTGTAAAAACTCATGTGAGTAATATTTT
AAGTAAATTGGAAGTTCAGGACCGTACTCAGGCTGTGATATATGCCTTTCAACATGGGTTAATAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment