Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | EP23_RS14350 | Genome accession | NZ_CP009623 |
| Coordinates | 453856..454737 (+) | Length | 293 a.a. |
| NCBI ID | WP_060550902.1 | Uniprot ID | - |
| Organism | Staphylococcus agnetis strain 908 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 421349..488201 | 453856..454737 | within | 0 |
Gene organization within MGE regions
Location: 421349..488201
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EP23_RS14205 (EP23_02125) | fakA | 421525..423183 (+) | 1659 | WP_037564742.1 | fatty acid kinase catalytic subunit FakA | - |
| EP23_RS14210 (EP23_02130) | sdaAB | 423345..424010 (+) | 666 | WP_060552470.1 | L-serine ammonia-lyase, iron-sulfur-dependent subunit beta | - |
| EP23_RS14215 (EP23_02135) | sdaAA | 424028..424897 (+) | 870 | WP_060550883.1 | L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha | - |
| EP23_RS14220 (EP23_02140) | recG | 424899..426944 (+) | 2046 | WP_060550884.1 | ATP-dependent DNA helicase RecG | - |
| EP23_RS14225 (EP23_02145) | fapR | 427203..427763 (+) | 561 | WP_060550885.1 | transcription factor FapR | - |
| EP23_RS14230 (EP23_02150) | plsX | 427765..428751 (+) | 987 | WP_060550886.1 | phosphate acyltransferase PlsX | - |
| EP23_RS14235 (EP23_02155) | fabD | 428744..429670 (+) | 927 | WP_060550887.1 | ACP S-malonyltransferase | - |
| EP23_RS14240 (EP23_02160) | fabG | 429663..430400 (+) | 738 | WP_060550888.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| EP23_RS14245 (EP23_02165) | - | 430717..430950 (+) | 234 | WP_019165520.1 | acyl carrier protein | - |
| EP23_RS14250 (EP23_02170) | rnc | 431062..431793 (+) | 732 | WP_060550889.1 | ribonuclease III | - |
| EP23_RS14255 (EP23_02175) | smc | 431797..435363 (+) | 3567 | WP_060550890.1 | chromosome segregation protein SMC | - |
| EP23_RS14260 (EP23_02180) | ftsY | 435364..436695 (+) | 1332 | WP_060550891.1 | signal recognition particle-docking protein FtsY | - |
| EP23_RS14265 (EP23_02185) | - | 436682..437014 (+) | 333 | WP_037564722.1 | putative DNA-binding protein | - |
| EP23_RS14270 (EP23_02190) | ffh | 437028..438395 (+) | 1368 | WP_060550892.1 | signal recognition particle protein | - |
| EP23_RS14275 (EP23_02195) | rpsP | 438621..438896 (+) | 276 | WP_037564718.1 | 30S ribosomal protein S16 | - |
| EP23_RS14280 (EP23_02200) | rimM | 439001..439504 (+) | 504 | WP_060550893.1 | ribosome maturation factor RimM | - |
| EP23_RS14285 (EP23_02205) | trmD | 439501..440235 (+) | 735 | WP_060550894.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| EP23_RS14290 (EP23_02210) | rplS | 440340..440690 (+) | 351 | WP_060550895.1 | 50S ribosomal protein L19 | - |
| EP23_RS14295 (EP23_02215) | - | 440973..441656 (+) | 684 | WP_082624718.1 | phosphatase PAP2 family protein | - |
| EP23_RS14300 (EP23_02220) | - | 441797..442186 (+) | 390 | WP_060550897.1 | hypothetical protein | - |
| EP23_RS14305 (EP23_02225) | - | 442176..443417 (+) | 1242 | WP_060550898.1 | SpaA isopeptide-forming pilin-related protein | - |
| EP23_RS14310 (EP23_02230) | - | 443527..446121 (-) | 2595 | WP_253724560.1 | YfhO family protein | - |
| EP23_RS14315 (EP23_02235) | - | 446118..448712 (-) | 2595 | WP_060552472.1 | YfhO family protein | - |
| EP23_RS14320 (EP23_02240) | - | 448740..449102 (-) | 363 | WP_105995858.1 | GtrA family protein | - |
| EP23_RS14325 (EP23_02245) | ylqF | 449331..450212 (+) | 882 | WP_060552473.1 | ribosome biogenesis GTPase YlqF | - |
| EP23_RS14330 (EP23_02250) | - | 450202..450978 (+) | 777 | WP_060550900.1 | ribonuclease HII | - |
| EP23_RS14335 (EP23_02255) | - | 451065..451334 (+) | 270 | WP_037564707.1 | hypothetical protein | - |
| EP23_RS14340 (EP23_02260) | sucC | 451547..452713 (+) | 1167 | WP_037564702.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| EP23_RS14345 (EP23_02265) | sucD | 452735..453643 (+) | 909 | WP_060550901.1 | succinate--CoA ligase subunit alpha | - |
| EP23_RS14350 (EP23_02270) | dprA | 453856..454737 (+) | 882 | WP_060550902.1 | DNA-processing protein DprA | Machinery gene |
| EP23_RS14355 (EP23_02275) | topA | 454832..456901 (+) | 2070 | WP_060550903.1 | type I DNA topoisomerase | - |
| EP23_RS14360 (EP23_02280) | trmFO | 456914..458218 (+) | 1305 | WP_060550904.1 | FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO | - |
| EP23_RS14365 (EP23_02285) | xerC | 458369..459229 (+) | 861 | WP_420894723.1 | tyrosine recombinase XerC | - |
| EP23_RS14370 (EP23_02290) | hslV | 459233..459775 (+) | 543 | WP_060550906.1 | ATP-dependent protease subunit HslV | - |
| EP23_RS14375 (EP23_02295) | hslU | 459792..461201 (+) | 1410 | WP_060550907.1 | ATP-dependent protease ATPase subunit HslU | - |
| EP23_RS14380 (EP23_02300) | codY | 461216..461989 (+) | 774 | WP_060550908.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| EP23_RS14385 (EP23_02305) | rpsB | 462151..462927 (+) | 777 | WP_037564683.1 | 30S ribosomal protein S2 | - |
| EP23_RS14390 (EP23_02310) | tsf | 463098..463979 (+) | 882 | WP_171509145.1 | translation elongation factor Ts | - |
| EP23_RS14395 (EP23_02315) | pyrH | 464133..464855 (+) | 723 | WP_037564679.1 | UMP kinase | - |
| EP23_RS14400 (EP23_02320) | frr | 464874..465428 (+) | 555 | WP_037564677.1 | ribosome recycling factor | - |
| EP23_RS14405 (EP23_02325) | - | 465578..466339 (+) | 762 | WP_037564674.1 | isoprenyl transferase | - |
| EP23_RS14410 (EP23_02330) | - | 466353..467132 (+) | 780 | WP_060550909.1 | phosphatidate cytidylyltransferase | - |
| EP23_RS14415 (EP23_02335) | - | 467148..468278 (+) | 1131 | WP_060550910.1 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase | - |
| EP23_RS14420 (EP23_02340) | rseP | 468285..469565 (+) | 1281 | WP_060550911.1 | RIP metalloprotease RseP | - |
| EP23_RS14425 (EP23_02345) | - | 469594..471300 (+) | 1707 | WP_060550912.1 | proline--tRNA ligase | - |
| EP23_RS14430 (EP23_02350) | - | 471499..475809 (+) | 4311 | WP_060550913.1 | PolC-type DNA polymerase III | - |
| EP23_RS14435 (EP23_02355) | rimP | 475937..476404 (+) | 468 | WP_060550914.1 | ribosome maturation factor RimP | - |
| EP23_RS14440 (EP23_02360) | nusA | 476424..477456 (+) | 1033 | Protein_470 | transcription termination factor NusA | - |
| EP23_RS14445 (EP23_02365) | rnpM | 477614..477901 (+) | 288 | WP_037564655.1 | RNase P modulator RnpM | - |
| EP23_RS14450 (EP23_02370) | - | 477898..478200 (+) | 303 | WP_060550915.1 | YlxQ family RNA-binding protein | - |
| EP23_RS14455 (EP23_02375) | infB | 478217..480349 (+) | 2133 | WP_060550916.1 | translation initiation factor IF-2 | - |
| EP23_RS14460 (EP23_02380) | - | 480544..480930 (+) | 387 | WP_241955026.1 | VOC family protein | - |
| EP23_RS14465 (EP23_02385) | rbfA | 481028..481372 (+) | 345 | WP_037564645.1 | 30S ribosome-binding factor RbfA | - |
| EP23_RS14470 (EP23_02390) | truB | 481446..482363 (+) | 918 | WP_060550918.1 | tRNA pseudouridine(55) synthase TruB | - |
| EP23_RS14475 (EP23_02395) | - | 482378..483349 (+) | 972 | WP_060550919.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| EP23_RS14480 (EP23_02400) | rpsO | 483453..483722 (+) | 270 | WP_037564639.1 | 30S ribosomal protein S15 | - |
| EP23_RS14485 (EP23_02405) | pnp | 483891..485993 (+) | 2103 | WP_060550920.1 | polyribonucleotide nucleotidyltransferase | - |
| EP23_RS14490 (EP23_02410) | - | 486363..487679 (+) | 1317 | WP_060550921.1 | M30 family zinc metallopeptidase | - |
Sequence
Protein
Download Length: 293 a.a. Molecular weight: 33179.64 Da Isoelectric Point: 9.5876
>NTDB_id=130819 EP23_RS14350 WP_060550902.1 453856..454737(+) (dprA) [Staphylococcus agnetis strain 908]
MLLENLIKLRYAGFTTQQLYRIFKRPIDVLSSDITPILHQYITHQSPSSLRLKLQTFHTLSASDILQQLRHDNIFPITIL
DEQFPTLLKEIYQPPLLLFCKGDLTHVTISKYKLGIVGARDCTLYSEKAVNYLLHEMKHAPLIIVSGLAKGTDALAHDYA
LKYSLPTIGVLGFGHHYHYPSVTKSLRHTIEMNRRGLTISEYPPMTPPAKFRFPERNRIISGLSHGVLVTEAKEKSGALI
TLDQALEHNRNVYVLPGDMFNKHTKGNMMRIKEGAEIVLSAADILKDLNTSIQ
MLLENLIKLRYAGFTTQQLYRIFKRPIDVLSSDITPILHQYITHQSPSSLRLKLQTFHTLSASDILQQLRHDNIFPITIL
DEQFPTLLKEIYQPPLLLFCKGDLTHVTISKYKLGIVGARDCTLYSEKAVNYLLHEMKHAPLIIVSGLAKGTDALAHDYA
LKYSLPTIGVLGFGHHYHYPSVTKSLRHTIEMNRRGLTISEYPPMTPPAKFRFPERNRIISGLSHGVLVTEAKEKSGALI
TLDQALEHNRNVYVLPGDMFNKHTKGNMMRIKEGAEIVLSAADILKDLNTSIQ
Nucleotide
Download Length: 882 bp
>NTDB_id=130819 EP23_RS14350 WP_060550902.1 453856..454737(+) (dprA) [Staphylococcus agnetis strain 908]
GTGCTATTAGAAAATTTAATCAAATTGCGATATGCAGGTTTCACGACACAGCAACTTTATCGTATTTTTAAGCGACCTAT
TGACGTTTTGTCATCAGACATCACACCTATTTTGCATCAATATATTACGCACCAAAGTCCTTCTTCGTTACGATTAAAAC
TCCAAACATTTCATACATTAAGTGCTTCTGATATTTTACAACAACTTCGTCACGACAACATTTTTCCAATCACCATATTA
GATGAGCAATTCCCAACACTTTTAAAAGAAATTTACCAACCGCCACTTTTATTATTTTGTAAAGGCGACCTGACACACGT
TACCATTTCTAAGTACAAACTCGGCATAGTGGGTGCACGTGACTGTACGCTTTATAGCGAAAAAGCTGTCAATTATCTTC
TTCATGAGATGAAACACGCACCTTTAATCATTGTATCTGGTCTTGCGAAAGGAACAGATGCACTTGCGCATGATTATGCG
CTCAAATATTCATTACCTACAATAGGTGTGTTAGGGTTTGGGCATCATTATCATTATCCTTCAGTAACAAAATCACTTCG
ACACACAATTGAAATGAACCGACGAGGATTAACTATTAGTGAATATCCTCCTATGACGCCACCCGCAAAATTCCGTTTTC
CTGAACGTAATCGTATAATCAGTGGTCTGAGCCATGGCGTTCTAGTTACAGAAGCAAAAGAGAAAAGTGGTGCACTTATC
ACGTTAGATCAAGCATTAGAACATAATCGAAATGTGTATGTACTCCCTGGAGATATGTTTAATAAACACACAAAAGGTAA
TATGATGCGTATTAAGGAAGGTGCTGAAATTGTACTTTCAGCAGCAGATATTTTGAAAGATTTGAATACGTCAATTCAGT
GA
GTGCTATTAGAAAATTTAATCAAATTGCGATATGCAGGTTTCACGACACAGCAACTTTATCGTATTTTTAAGCGACCTAT
TGACGTTTTGTCATCAGACATCACACCTATTTTGCATCAATATATTACGCACCAAAGTCCTTCTTCGTTACGATTAAAAC
TCCAAACATTTCATACATTAAGTGCTTCTGATATTTTACAACAACTTCGTCACGACAACATTTTTCCAATCACCATATTA
GATGAGCAATTCCCAACACTTTTAAAAGAAATTTACCAACCGCCACTTTTATTATTTTGTAAAGGCGACCTGACACACGT
TACCATTTCTAAGTACAAACTCGGCATAGTGGGTGCACGTGACTGTACGCTTTATAGCGAAAAAGCTGTCAATTATCTTC
TTCATGAGATGAAACACGCACCTTTAATCATTGTATCTGGTCTTGCGAAAGGAACAGATGCACTTGCGCATGATTATGCG
CTCAAATATTCATTACCTACAATAGGTGTGTTAGGGTTTGGGCATCATTATCATTATCCTTCAGTAACAAAATCACTTCG
ACACACAATTGAAATGAACCGACGAGGATTAACTATTAGTGAATATCCTCCTATGACGCCACCCGCAAAATTCCGTTTTC
CTGAACGTAATCGTATAATCAGTGGTCTGAGCCATGGCGTTCTAGTTACAGAAGCAAAAGAGAAAAGTGGTGCACTTATC
ACGTTAGATCAAGCATTAGAACATAATCGAAATGTGTATGTACTCCCTGGAGATATGTTTAATAAACACACAAAAGGTAA
TATGATGCGTATTAAGGAAGGTGCTGAAATTGTACTTTCAGCAGCAGATATTTTGAAAGATTTGAATACGTCAATTCAGT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus MW2 |
51.228 |
97.27 |
0.498 |
| dprA | Staphylococcus aureus N315 |
51.228 |
97.27 |
0.498 |
| dprA | Streptococcus mutans UA159 |
36.149 |
100 |
0.365 |