Detailed information NTG0130197

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FORC1_RS10120
• Genome accession: NZ_CP009554
• Coordinates: 2036912..2037955 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FORC_001
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2031912..2042955

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC1_RS10090 (FORC1_1829)	-	2032333..2033589 (-)	1257	WP_001793983.1	aminopeptidase	-
FORC1_RS10095 (FORC1_1830)	-	2033592..2033792 (-)	201	WP_000180460.1	DUF1128 family protein	-
FORC1_RS10100 (FORC1_1831)	-	2033939..2034403 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
FORC1_RS10105 (FORC1_1832)	-	2034410..2034685 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FORC1_RS10110 (FORC1_1833)	-	2034963..2036180 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
FORC1_RS10115 (FORC1_1834)	vraR	2036293..2036922 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
FORC1_RS10120 (FORC1_1835)	vraS	2036912..2037955 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FORC1_RS10125 (FORC1_1836)	liaF	2037952..2038650 (-)	699	WP_042363640.1	cell wall-active antibiotics response protein LiaF	-
FORC1_RS10130 (FORC1_1837)	-	2038665..2039051 (-)	387	WP_001110178.1	hypothetical protein	-
FORC1_RS10135 (FORC1_1838)	map	2039268..2040026 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FORC1_RS10140 (FORC1_1839)	-	2040726..2041712 (+)	987	WP_001014423.1	FUSC family protein	-
FORC1_RS10145 (FORC1_1840)	-	2041901..2042314 (-)	414	WP_001643743.1	hypothetical protein	-
FORC1_RS10150	-	2042343..2042453 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=130197 FORC1_RS10120 WP_001017131.1 2036912..2037955(-) (vraS) [Staphylococcus aureus strain FORC_001]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=130197 FORC1_RS10120 WP_001017131.1 2036912..2037955(-) (vraS) [Staphylococcus aureus strain FORC_001]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1