Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   SpyM6JRS4_RS08640 Genome accession   NZ_CP011414
Coordinates   1742121..1742717 (-) Length   198 a.a.
NCBI ID   WP_011185063.1    Uniprot ID   A2RGV1
Organism   Streptococcus pyogenes JRS4     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1737121..1747717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SpyM6JRS4_RS08605 (SpyM6JRS4_08600) - 1737182..1737487 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  SpyM6JRS4_RS08610 (SpyM6JRS4_08605) ruvX 1737499..1737918 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  SpyM6JRS4_RS08615 (SpyM6JRS4_08610) - 1737915..1738184 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  SpyM6JRS4_RS08620 (SpyM6JRS4_08615) spx 1738297..1738695 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  SpyM6JRS4_RS08625 (SpyM6JRS4_08620) recA 1738986..1740122 (-) 1137 WP_002982186.1 recombinase RecA Machinery gene
  SpyM6JRS4_RS08630 (SpyM6JRS4_08625) cinA 1740211..1741482 (-) 1272 WP_011185061.1 competence/damage-inducible protein A Machinery gene
  SpyM6JRS4_RS08635 (SpyM6JRS4_08630) - 1741551..1742111 (-) 561 WP_021340449.1 DNA-3-methyladenine glycosylase I -
  SpyM6JRS4_RS08640 (SpyM6JRS4_08635) ruvA 1742121..1742717 (-) 597 WP_011185063.1 Holliday junction branch migration protein RuvA Machinery gene
  SpyM6JRS4_RS08645 (SpyM6JRS4_08640) - 1742719..1743939 (-) 1221 WP_011018316.1 MFS transporter -
  SpyM6JRS4_RS08650 (SpyM6JRS4_08645) hexB 1743950..1745932 (-) 1983 WP_027968888.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21852.19 Da        Isoelectric Point: 6.4948

>NTDB_id=127969 SpyM6JRS4_RS08640 WP_011185063.1 1742121..1742717(-) (ruvA) [Streptococcus pyogenes JRS4]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=127969 SpyM6JRS4_RS08640 WP_011185063.1 1742121..1742717(-) (ruvA) [Streptococcus pyogenes JRS4]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGCATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.394

100

0.414