Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ECVR50_RS19165 Genome accession   NZ_CP011134
Coordinates   3802684..3803316 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli VR50     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3797684..3808316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECVR50_RS19135 (ECVR50_3762) yheS 3797853..3799766 (+) 1914 WP_000634841.1 ABC transporter ATP-binding protein -
  ECVR50_RS19140 (ECVR50_3763) yheT 3799766..3800788 (+) 1023 WP_000057361.1 hydrolase -
  ECVR50_RS19145 (ECVR50_3764) yheU 3800782..3801000 (+) 219 WP_000907085.1 YheU family protein -
  ECVR50_RS19150 (ECVR50_3765) prkB 3801054..3801923 (+) 870 WP_001274680.1 phosphoribulokinase -
  ECVR50_RS19155 (ECVR50_3766) yhfA 3801978..3802382 (-) 405 WP_001148908.1 OsmC family protein -
  ECVR50_RS19165 (ECVR50_3767) crp 3802684..3803316 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  ECVR50_RS19170 (ECVR50_3768) yhfK 3803367..3805457 (+) 2091 WP_046072896.1 YccS/YhfK family putative transporter -
  ECVR50_RS19175 (ECVR50_3769) argD 3805524..3806744 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ECVR50_RS19180 (ECVR50_3770) pabA 3806830..3807393 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  ECVR50_RS19185 (ECVR50_3771) fic 3807425..3808027 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  ECVR50_RS19190 (ECVR50_3772) yhfG 3808017..3808184 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=126467 ECVR50_RS19165 WP_000242755.1 3802684..3803316(+) (crp) [Escherichia coli VR50]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=126467 ECVR50_RS19165 WP_000242755.1 3802684..3803316(+) (crp) [Escherichia coli VR50]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment