Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ID09_RS03275 Genome accession   NZ_CP008921
Coordinates   676484..677833 (+) Length   449 a.a.
NCBI ID   WP_024379730.1    Uniprot ID   A0A0Z8J8V5
Organism   Streptococcus suis 6407     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 671484..682833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS03250 (ID09_03300) - 672595..673254 (-) 660 WP_002935828.1 amino acid ABC transporter permease -
  ID09_RS03255 (ID09_03305) - 673269..673967 (-) 699 WP_024382219.1 amino acid ABC transporter permease -
  ID09_RS03260 (ID09_03310) - 673982..674821 (-) 840 WP_024382220.1 transporter substrate-binding domain-containing protein -
  ID09_RS03265 (ID09_03315) - 674832..675593 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  ID09_RS03270 (ID09_03320) micA 675787..676491 (+) 705 WP_015646623.1 response regulator YycF Regulator
  ID09_RS03275 (ID09_03325) micB 676484..677833 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ID09_RS03280 (ID09_03330) vicX 677840..678643 (+) 804 WP_024382223.1 MBL fold metallo-hydrolase Regulator
  ID09_RS03285 (ID09_03335) - 679270..680472 (-) 1203 WP_079376556.1 IS110 family transposase -
  ID09_RS03290 (ID09_03340) - 680781..681305 (+) 525 WP_235181377.1 ATP-binding cassette domain-containing protein -
  ID09_RS12320 - 681593..681955 (+) 363 WP_050571059.1 hypothetical protein -
  ID09_RS12325 - 681982..682326 (+) 345 WP_235181378.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51035.09 Da        Isoelectric Point: 4.5202

>NTDB_id=125694 ID09_RS03275 WP_024379730.1 676484..677833(+) (micB) [Streptococcus suis 6407]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=125694 ID09_RS03275 WP_024379730.1 676484..677833(+) (micB) [Streptococcus suis 6407]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTGGACATGAGGGGAAGTCCTGAAATCACAGATATGGCTAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATTCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCATCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCACGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8J8V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment