Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   VAB027_RS06400 Genome accession   NZ_CP010812
Coordinates   1375997..1376629 (-) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A067BGB0
Organism   Vibrio cholerae strain 10432-62     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370997..1381629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAB027_RS06375 (VAB027_1252) - 1371999..1372553 (+) 555 WP_046126410.1 outer membrane beta-barrel protein -
  VAB027_RS06380 (VAB027_1253) uraH 1373312..1373695 (+) 384 WP_000779472.1 hydroxyisourate hydrolase -
  VAB027_RS06385 (VAB027_1254) - 1373708..1374211 (+) 504 WP_000700649.1 heme-binding protein -
  VAB027_RS06395 (VAB027_1255) - 1374612..1375934 (+) 1323 WP_046126018.1 IS4 family transposase -
  VAB027_RS06400 (VAB027_1256) crp 1375997..1376629 (-) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  VAB027_RS06405 (VAB027_1257) - 1376872..1377741 (-) 870 WP_001274667.1 phosphoribulokinase -
  VAB027_RS06410 (VAB027_1258) - 1377838..1378047 (-) 210 WP_001888622.1 YheU family protein -
  VAB027_RS06415 (VAB027_1259) - 1378176..1379165 (-) 990 WP_046126411.1 hydrolase -
  VAB027_RS06420 (VAB027_1260) - 1379162..1379647 (-) 486 WP_001278732.1 TIGR02444 family protein -
  VAB027_RS06425 (VAB027_1261) - 1379648..1381564 (-) 1917 WP_046126412.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=124498 VAB027_RS06400 WP_000242749.1 1375997..1376629(-) (crp) [Vibrio cholerae strain 10432-62]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=124498 VAB027_RS06400 WP_000242749.1 1375997..1376629(-) (crp) [Vibrio cholerae strain 10432-62]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAGTTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGATGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAAAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterProScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A067BGB0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467