Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   RU53_RS09440 Genome accession   NZ_CP010526
Coordinates   1894858..1895847 (-) Length   329 a.a.
NCBI ID   WP_000219066.1    Uniprot ID   P67655
Organism   Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1889858..1900847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RU53_RS09425 (RU53_1830) acsA 1891059..1892765 (-) 1707 WP_000862094.1 acetate--CoA ligase -
  RU53_RS09430 (RU53_1831) - 1892934..1893566 (+) 633 WP_001016013.1 hypothetical protein -
  RU53_RS09435 (RU53_1832) - 1893591..1894760 (+) 1170 WP_001184005.1 acetoin utilization protein AcuC -
  RU53_RS09440 (RU53_1833) ccpA 1894858..1895847 (-) 990 WP_000219066.1 catabolite control protein A Regulator
  RU53_RS15450 - 1895920..1896033 (-) 114 WP_001788994.1 hypothetical protein -
  RU53_RS09450 (RU53_1834) - 1896387..1897478 (-) 1092 WP_000066384.1 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase -
  RU53_RS15455 - 1897939..1898022 (-) 84 WP_031867535.1 hypothetical protein -
  RU53_RS09460 (RU53_1835) - 1898414..1900060 (+) 1647 WP_040968907.1 IS1182 family transposase -

Sequence

Protein


Download         Length: 329 a.a.        Molecular weight: 36060.24 Da        Isoelectric Point: 5.5054

>NTDB_id=124016 RU53_RS09440 WP_000219066.1 1894858..1895847(-) (ccpA) [Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide


Download         Length: 990 bp        

>NTDB_id=124016 RU53_RS09440 WP_000219066.1 1894858..1895847(-) (ccpA) [Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAAGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAAGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATCAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(4-49)

Periplasmic binding protein-like domain (Peripla_BP_3)

(171-328)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P67655

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

47.879

100

0.48
  ccpA Streptococcus gordonii str. Challis substr. CH1

47.112

100

0.471
  ccpA Streptococcus pneumoniae D39

46.201

100

0.462

Multiple sequence alignment