Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C645_RS05795 Genome accession   NZ_CP008740
Coordinates   1127455..1128129 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae 2019     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1122455..1133129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C645_RS05760 (C645_05840) rpmG 1123371..1123541 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  C645_RS05765 (C645_05845) rpmB 1123553..1123789 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  C645_RS05770 (C645_05850) radC 1124003..1124668 (-) 666 WP_013527272.1 RadC family protein -
  C645_RS05775 (C645_05855) coaBC 1124832..1126034 (+) 1203 WP_005655942.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  C645_RS05780 (C645_05860) dut 1126082..1126534 (+) 453 WP_005655943.1 dUTP diphosphatase -
  C645_RS05785 (C645_05865) slmA 1126541..1127197 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  C645_RS05790 (C645_05870) - 1127219..1127470 (+) 252 WP_005647999.1 YheU family protein -
  C645_RS05795 (C645_05875) crp 1127455..1128129 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  C645_RS05800 (C645_05880) rlmC 1128494..1129669 (-) 1176 WP_005655944.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  C645_RS05805 (C645_05885) nagZ 1129662..1130717 (-) 1056 WP_005688377.1 beta-N-acetylhexosaminidase -
  C645_RS05810 (C645_05890) - 1130721..1131071 (-) 351 WP_005688375.1 YcfL family protein -
  C645_RS05815 (C645_05895) hinT 1131071..1131421 (-) 351 WP_005688373.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=123972 C645_RS05795 WP_005647998.1 1127455..1128129(+) (crp) [Haemophilus influenzae 2019]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=123972 C645_RS05795 WP_005647998.1 1127455..1128129(+) (crp) [Haemophilus influenzae 2019]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAGGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCCACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment