Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   H733_RS07520 Genome accession   NZ_CP007805
Coordinates   1560137..1560811 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae CGSHiCZ412602     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1555137..1565811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H733_RS07500 (H733_1476) hinT 1556842..1557192 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  H733_RS07505 (H733_1477) - 1557192..1557542 (+) 351 WP_005647993.1 YcfL family protein -
  H733_RS07510 (H733_1478) nagZ 1557546..1558601 (+) 1056 WP_038440103.1 beta-N-acetylhexosaminidase -
  H733_RS07515 (H733_1479) rlmC 1558594..1559772 (+) 1179 WP_038440104.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  H733_RS07520 (H733_1480) crp 1560137..1560811 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  H733_RS07525 (H733_1481) - 1560796..1561047 (-) 252 WP_005647999.1 YheU family protein -
  H733_RS07530 (H733_1482) slmA 1561069..1561725 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  H733_RS07535 (H733_1483) dut 1561729..1562184 (-) 456 WP_005631431.1 dUTP diphosphatase -
  H733_RS07540 (H733_1484) coaBC 1562232..1563434 (-) 1203 WP_038440105.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  H733_RS07545 (H733_1485) radC 1563598..1564263 (+) 666 WP_032821549.1 RadC family protein -
  H733_RS07550 (H733_1486) rpmB 1564477..1564713 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  H733_RS07555 (H733_1487) rpmG 1564725..1564895 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=123500 H733_RS07520 WP_005647998.1 1560137..1560811(-) (crp) [Haemophilus influenzae CGSHiCZ412602]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=123500 H733_RS07520 WP_005647998.1 1560137..1560811(-) (crp) [Haemophilus influenzae CGSHiCZ412602]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment