Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   B6116_RS00760 Genome accession   NZ_CP007667
Coordinates   144501..144965 (-) Length   154 a.a.
NCBI ID   WP_014580830.1    Uniprot ID   -
Organism   Neisseria meningitidis strain B6116/77     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 138023..155015 144501..144965 within 0


Gene organization within MGE regions


Location: 138023..155015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B6116_RS00715 (B6116_00131) - 139515..139760 (-) 246 WP_002226028.1 hypothetical protein -
  B6116_RS00725 (B6116_00132) - 139872..140300 (+) 429 WP_002226027.1 CopD family protein -
  B6116_RS00730 (B6116_00133) - 140312..140788 (+) 477 WP_002226026.1 CYTH domain-containing protein -
  B6116_RS00735 (B6116_00134) - 141138..141626 (-) 489 WP_002226025.1 dihydrofolate reductase -
  B6116_RS00740 (B6116_00135) aroG 141694..142749 (-) 1056 WP_002226024.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  B6116_RS14335 - 142911..143138 (-) 228 WP_153310284.1 hypothetical protein -
  B6116_RS00750 (B6116_00136) - 143365..143673 (+) 309 WP_017629289.1 membrane protein -
  B6116_RS14625 - 143722..143826 (-) 105 Protein_135 IS1595 family transposase -
  B6116_RS00760 (B6116_00138) comE 144501..144965 (-) 465 WP_014580830.1 helix-hairpin-helix domain-containing protein Machinery gene
  B6116_RS00795 (B6116_00144) - 150763..151569 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  B6116_RS00800 (B6116_00145) ffh 151789..153159 (+) 1371 WP_002221448.1 signal recognition particle protein -
  B6116_RS00805 (B6116_00146) dsbA2 153490..154185 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  B6116_RS00810 (B6116_00147) - 154356..155015 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16519.75 Da        Isoelectric Point: 10.9695

>NTDB_id=122176 B6116_RS00760 WP_014580830.1 144501..144965(-) (comE) [Neisseria meningitidis strain B6116/77]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=122176 B6116_RS00760 WP_014580830.1 144501..144965(-) (comE) [Neisseria meningitidis strain B6116/77]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGGCCCGGCAAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment