Detailed information NTG0122174

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: B6116_RS00605
• Genome accession: NZ_CP007667
• Coordinates: 118446..119306 (+)
• Length: 286 a.a.
• NCBI ID: WP_002226036.1
• Uniprot ID: A0A112F5U3
• Organism: Neisseria meningitidis strain B6116/77
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113446..124306

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B6116_RS00590 (B6116_00107)	dapD	113956..114777 (-)	822	WP_002226039.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
B6116_RS11410	-	114787..115017 (-)	231	WP_002212338.1	hypothetical protein	-
B6116_RS00595 (B6116_00108)	pgi	114987..116630 (-)	1644	WP_002244409.1	glucose-6-phosphate isomerase	-
B6116_RS00600 (B6116_00109)	pilG	117140..118372 (+)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
B6116_RS00605 (B6116_00110)	pilD	118446..119306 (+)	861	WP_002226036.1	prepilin peptidase	Machinery gene
B6116_RS00610 (B6116_00111)	coaE	119308..119940 (+)	633	WP_002226034.1	dephospho-CoA kinase	-
B6116_RS00615 (B6116_00112)	-	119933..120142 (+)	210	WP_002226032.1	DNA gyrase inhibitor YacG	-
B6116_RS00620 (B6116_00113)	pilF	120227..121903 (-)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
B6116_RS00630 (B6116_00115)	-	122395..122841 (-)	447	WP_002233503.1	DUF441 domain-containing protein	-
B6116_RS00635 (B6116_00116)	ispB	122846..123820 (-)	975	WP_002216396.1	octaprenyl diphosphate synthase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31389.43 Da
• Isoelectric Point: 8.2213

>NTDB_id=122174 B6116_RS00605 WP_002226036.1 118446..119306(+) (pilD) [Neisseria meningitidis strain B6116/77]
MSDLSVLSPFAVPLTAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=122174 B6116_RS00605 WP_002226036.1 118446..119306(+) (pilD) [Neisseria meningitidis strain B6116/77]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGACAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

3D structure

• AlphaFold DB: A0A112F5U3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	95.789	99.65	0.955
pilD	Vibrio cholerae strain A1552	44.097	100	0.444
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434
pilD	Vibrio campbellii strain DS40M4	44.565	96.503	0.43