Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EN71_RS05380 Genome accession   NZ_CP007631
Coordinates   1038109..1039422 (-) Length   437 a.a.
NCBI ID   WP_000042570.1    Uniprot ID   A0A853P3V4
Organism   Streptococcus agalactiae strain NGBS061     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1033109..1044422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN71_RS05360 (EN72_05490) - 1034589..1035362 (-) 774 WP_000622398.1 DUF3307 domain-containing protein -
  EN71_RS05365 (EN72_05495) - 1035352..1036038 (-) 687 WP_000280308.1 SatD family protein -
  EN71_RS05370 (EN72_05500) ffh 1036105..1037670 (-) 1566 WP_000863589.1 signal recognition particle protein -
  EN71_RS05375 (EN72_05505) - 1037688..1038020 (-) 333 WP_000402075.1 putative DNA-binding protein -
  EN71_RS05380 (EN72_05510) ciaH 1038109..1039422 (-) 1314 WP_000042570.1 sensor histidine kinase Regulator
  EN71_RS05385 (EN72_05515) ciaR 1039406..1040086 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  EN71_RS05390 (EN72_05520) - 1040248..1042797 (-) 2550 WP_000859382.1 M1 family metallopeptidase -
  EN71_RS05395 (EN72_05525) phoU 1042943..1043596 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  EN71_RS05400 (EN72_05530) pstB 1043630..1044388 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49659.07 Da        Isoelectric Point: 9.3853

>NTDB_id=121845 EN71_RS05380 WP_000042570.1 1038109..1039422(-) (ciaH) [Streptococcus agalactiae strain NGBS061]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSHTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=121845 EN71_RS05380 WP_000042570.1 1038109..1039422(-) (ciaH) [Streptococcus agalactiae strain NGBS061]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACATACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A853P3V4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.606

98.169

0.595
  ciaH Streptococcus pneumoniae Rx1

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae D39

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae R6

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.905

96.11

0.499

Multiple sequence alignment