Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DK42_RS05420 Genome accession   NZ_CP007571
Coordinates   1073215..1074528 (-) Length   437 a.a.
NCBI ID   WP_000042577.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS2-NM     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068215..1079528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK42_RS05400 (DK42_05510) - 1069695..1070468 (-) 774 WP_000622398.1 DUF3307 domain-containing protein -
  DK42_RS05405 (DK42_05515) - 1070458..1071144 (-) 687 WP_000280308.1 SatD family protein -
  DK42_RS05410 (DK42_05520) ffh 1071211..1072776 (-) 1566 WP_000863589.1 signal recognition particle protein -
  DK42_RS05415 (DK42_05525) - 1072794..1073126 (-) 333 WP_000402075.1 putative DNA-binding protein -
  DK42_RS05420 (DK42_05530) ciaH 1073215..1074528 (-) 1314 WP_000042577.1 HAMP domain-containing sensor histidine kinase Regulator
  DK42_RS05425 (DK42_05535) ciaR 1074512..1075192 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  DK42_RS05430 (DK42_05540) - 1075354..1077903 (-) 2550 WP_000859382.1 M1 family metallopeptidase -
  DK42_RS05435 (DK42_05545) phoU 1078049..1078702 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  DK42_RS05440 (DK42_05550) pstB 1078736..1079494 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49678.07 Da        Isoelectric Point: 9.3896

>NTDB_id=121113 DK42_RS05420 WP_000042577.1 1073215..1074528(-) (ciaH) [Streptococcus agalactiae strain GBS2-NM]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPNLKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=121113 DK42_RS05420 WP_000042577.1 1073215..1074528(-) (ciaH) [Streptococcus agalactiae strain GBS2-NM]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAATTTAAAAGGTTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.373

98.169

0.593
  ciaH Streptococcus pneumoniae Rx1

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae D39

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae R6

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae TIGR4

52.143

96.11

0.501

Multiple sequence alignment