Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   SH04_RS20935 Genome accession   NZ_CP010443
Coordinates   4207274..4207906 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli K-12 strain K-12 MG1655     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4202274..4212906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SH04_RS20905 (SH04_20915) yheS 4202443..4204356 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  SH04_RS20910 (SH04_20920) yheT 4204356..4205378 (+) 1023 WP_000057356.1 hydrolase -
  SH04_RS20915 (SH04_20925) yheU 4205372..4205590 (+) 219 WP_000907085.1 YheU family protein -
  SH04_RS20920 (SH04_20930) prkB 4205644..4206513 (+) 870 WP_001274680.1 phosphoribulokinase -
  SH04_RS20925 (SH04_20935) yhfA 4206568..4206972 (-) 405 WP_001148908.1 OsmC family protein -
  SH04_RS20935 (SH04_20945) crp 4207274..4207906 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  SH04_RS20940 (SH04_20950) yhfK 4207957..4210047 (+) 2091 WP_021553919.1 YccS/YhfK family putative transporter -
  SH04_RS20945 (SH04_20955) argD 4210114..4211334 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  SH04_RS20950 (SH04_20960) pabA 4211420..4211983 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  SH04_RS20955 (SH04_20965) fic 4212015..4212617 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  SH04_RS20960 (SH04_20970) yhfG 4212607..4212774 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=121079 SH04_RS20935 WP_000242755.1 4207274..4207906(+) (crp) [Escherichia coli K-12 strain K-12 MG1655]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=121079 SH04_RS20935 WP_000242755.1 4207274..4207906(+) (crp) [Escherichia coli K-12 strain K-12 MG1655]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment