Detailed information NTG0120956

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DK93_RS06345
• Genome accession: NZ_CP007562
• Coordinates: 1299692..1300693 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NGAS327
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1294692..1305693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK93_RS06330 (DK93_06515)	thrS	1294862..1296805 (-)	1944	WP_012560525.1	threonine--tRNA ligase	-
DK93_RS06335 (DK93_06525)	-	1297227..1298561 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
DK93_RS06340 (DK93_06530)	-	1298563..1299561 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DK93_RS06345 (DK93_06535)	ccpA	1299692..1300693 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DK93_RS06350 (DK93_06540)	-	1300867..1301952 (+)	1086	WP_012560524.1	aminopeptidase P family protein	-
DK93_RS06355 (DK93_06545)	-	1302001..1302666 (+)	666	WP_012560523.1	NAD(P)H-dependent oxidoreductase	-
DK93_RS06360 (DK93_06550)	-	1302677..1303054 (+)	378	WP_002985686.1	VOC family protein	-
DK93_RS06365 (DK93_06555)	-	1303199..1304125 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DK93_RS06370 (DK93_06560)	-	1304336..1305019 (+)	684	WP_038431232.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=120956 DK93_RS06345 WP_002985680.1 1299692..1300693(-) (ccpA) [Streptococcus pyogenes strain NGAS327]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=120956 DK93_RS06345 WP_002985680.1 1299692..1300693(-) (ccpA) [Streptococcus pyogenes strain NGAS327]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTTGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559