Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   SH05_RS21045 Genome accession   NZ_CP010438
Coordinates   4220144..4220776 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli K-12 strain K-12 MG1655     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4215144..4225776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SH05_RS21015 (SH05_21030) yheS 4215313..4217226 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  SH05_RS21020 (SH05_21035) yheT 4217226..4218248 (+) 1023 WP_000057356.1 hydrolase -
  SH05_RS21025 (SH05_21040) yheU 4218242..4218460 (+) 219 WP_000907085.1 YheU family protein -
  SH05_RS21030 (SH05_21045) prkB 4218514..4219383 (+) 870 WP_001274680.1 phosphoribulokinase -
  SH05_RS21035 (SH05_21050) yhfA 4219438..4219842 (-) 405 WP_001148908.1 OsmC family protein -
  SH05_RS21045 (SH05_21060) crp 4220144..4220776 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  SH05_RS21050 (SH05_21065) yhfK 4220827..4222917 (+) 2091 WP_021553919.1 YccS/YhfK family putative transporter -
  SH05_RS21055 (SH05_21070) argD 4222984..4224204 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  SH05_RS21060 (SH05_21075) pabA 4224290..4224853 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  SH05_RS21065 (SH05_21080) fic 4224885..4225487 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  SH05_RS21070 (SH05_21085) yhfG 4225477..4225644 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=120679 SH05_RS21045 WP_000242755.1 4220144..4220776(+) (crp) [Escherichia coli K-12 strain K-12 MG1655]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=120679 SH05_RS21045 WP_000242755.1 4220144..4220776(+) (crp) [Escherichia coli K-12 strain K-12 MG1655]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment