Detailed information NTG0120642

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPAP1_RS07745
• Genome accession: NZ_CP007537
• Coordinates: 1500966..1501967 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain AP1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1495966..1506967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPAP1_RS07730 (SPAP1_07720)	thrS	1496136..1498079 (-)	1944	WP_010921984.1	threonine--tRNA ligase	-
SPAP1_RS07735 (SPAP1_07725)	-	1498501..1499835 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
SPAP1_RS07740 (SPAP1_07730)	-	1499837..1500835 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
SPAP1_RS07745 (SPAP1_07735)	ccpA	1500966..1501967 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
SPAP1_RS07750 (SPAP1_07740)	-	1502141..1503226 (+)	1086	WP_002985682.1	Xaa-Pro peptidase family protein	-
SPAP1_RS07755 (SPAP1_07745)	-	1503275..1503940 (+)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
SPAP1_RS07760 (SPAP1_07750)	-	1503951..1504328 (+)	378	WP_002985686.1	VOC family protein	-
SPAP1_RS07765 (SPAP1_07755)	-	1504473..1505399 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
SPAP1_RS07770 (SPAP1_07760)	-	1505610..1506293 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=120642 SPAP1_RS07745 WP_002985680.1 1500966..1501967(-) (ccpA) [Streptococcus pyogenes strain AP1]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=120642 SPAP1_RS07745 WP_002985680.1 1500966..1501967(-) (ccpA) [Streptococcus pyogenes strain AP1]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559