Detailed information NTG0119785

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: NTHI723_RS06940
• Genome accession: NZ_CP007472
• Coordinates: 1391478..1392170 (+)
• Length: 230 a.a.
• NCBI ID: WP_038440789.1
• Uniprot ID: A0AAJ8WR53
• Organism: Haemophilus influenzae strain 723
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1386478..1397170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NTHI723_RS06920 (NTHI723_01392)	ampD	1387755..1388309 (-)	555	WP_044364862.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
NTHI723_RS06925 (NTHI723_01393)	pilA	1388424..1388873 (+)	450	WP_044364865.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
NTHI723_RS06930 (NTHI723_01394)	pilB	1388870..1390264 (+)	1395	WP_044364868.1	GspE/PulE family protein	Machinery gene
NTHI723_RS06935 (NTHI723_01395)	pilC	1390261..1391481 (+)	1221	WP_011271971.1	type II secretion system F family protein	Machinery gene
NTHI723_RS06940 (NTHI723_01396)	pilD	1391478..1392170 (+)	693	WP_038440789.1	A24 family peptidase	Machinery gene
NTHI723_RS06945 (NTHI723_01397)	rho	1392224..1393486 (-)	1263	WP_005629550.1	transcription termination factor Rho	-
NTHI723_RS06950 (NTHI723_01398)	metJ	1393734..1394051 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
NTHI723_RS06955 (NTHI723_01399)	cueR	1394065..1394451 (-)	387	WP_005663006.1	Cu(I)-responsive transcriptional regulator	-
NTHI723_RS06960 (NTHI723_01400)	-	1394528..1394734 (+)	207	WP_012054944.1	heavy-metal-associated domain-containing protein	-
NTHI723_RS06965 (NTHI723_01401)	-	1394820..1395026 (+)	207	WP_005648955.1	heavy-metal-associated domain-containing protein	-
NTHI723_RS06970 (NTHI723_01402)	-	1395112..1395318 (+)	207	WP_012054944.1	heavy-metal-associated domain-containing protein	-
NTHI723_RS06975 (NTHI723_01403)	-	1395404..1395610 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26786.77 Da
• Isoelectric Point: 8.6895

>NTDB_id=119785 NTHI723_RS06940 WP_038440789.1 1391478..1392170(+) (pilD) [Haemophilus influenzae strain 723]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide

• Length: 693 bp

>NTDB_id=119785 NTHI723_RS06940 WP_038440789.1 1391478..1392170(+) (pilD) [Haemophilus influenzae strain 723]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (92-199)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Haemophilus influenzae 86-028NP	97.391	100	0.974
pilD	Haemophilus influenzae Rd KW20	95.652	100	0.957