Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE1/comEA   Type   Machinery gene
Locus tag   NTHI723_RS03010 Genome accession   NZ_CP007472
Coordinates   623080..623427 (-) Length   115 a.a.
NCBI ID   WP_005690826.1    Uniprot ID   Q4QLQ4
Organism   Haemophilus influenzae strain 723     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 618080..628427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI723_RS02990 (NTHI723_00604) bioB 618469..619470 (-) 1002 WP_005655985.1 biotin synthase BioB -
  NTHI723_RS02995 (NTHI723_00605) thiQ 619583..620230 (-) 648 WP_038441405.1 thiamine ABC transporter ATP-binding protein -
  NTHI723_RS03000 (NTHI723_00606) thiP 620214..621830 (-) 1617 WP_011272346.1 thiamine/thiamine pyrophosphate ABC transporter permease -
  NTHI723_RS03005 (NTHI723_00607) thiB 621835..622833 (-) 999 WP_011272345.1 thiamine ABC transporter substrate binding subunit -
  NTHI723_RS03010 (NTHI723_00608) comE1/comEA 623080..623427 (-) 348 WP_005690826.1 helix-hairpin-helix domain-containing protein Machinery gene
  NTHI723_RS03015 (NTHI723_00609) ispH 623597..624541 (-) 945 WP_005659294.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  NTHI723_RS03020 (NTHI723_00610) lspA 624538..625053 (-) 516 WP_038441408.1 signal peptidase II -
  NTHI723_RS03025 (NTHI723_00611) - 625123..626682 (-) 1560 WP_038441409.1 phosphoethanolamine transferase -

Sequence

Protein


Download         Length: 115 a.a.        Molecular weight: 12479.38 Da        Isoelectric Point: 8.0084

>NTDB_id=119758 NTHI723_RS03010 WP_005690826.1 623080..623427(-) (comE1/comEA) [Haemophilus influenzae strain 723]
MKLMKTLFTSFVLCGSLAAGSTFAEDKVVEQTTQAVVTTQTDSQVAPAMMGDKLNINIATASEIQKSLTGIGAKKAEAIV
QYREKHGNFTNVEQLLEVQGIGKATLEKNRDRIIF

Nucleotide


Download         Length: 348 bp        

>NTDB_id=119758 NTHI723_RS03010 WP_005690826.1 623080..623427(-) (comE1/comEA) [Haemophilus influenzae strain 723]
ATGAAATTAATGAAAACATTATTCACTTCGTTTGTATTGTGTGGGTCACTTGCAGCTGGTTCCACTTTTGCTGAAGACAA
GGTGGTTGAGCAAACAACTCAAGCTGTTGTGACCACTCAAACGGATTCACAAGTAGCACCAGCTATGATGGGAGATAAAT
TGAATATTAACATAGCAACTGCCAGTGAAATTCAAAAATCCCTAACTGGCATTGGTGCGAAAAAAGCGGAAGCTATTGTG
CAATATCGTGAAAAACACGGTAATTTTACTAATGTAGAACAGCTTTTAGAAGTACAAGGAATTGGCAAAGCAACACTAGA
GAAAAATCGTGATCGTATAATCTTTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLQ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

81.25

97.391

0.791
  comEA/comE1 Glaesserella parasuis strain SC1401

57.944

93.043

0.539
  comEA Vibrio campbellii strain DS40M4

38.393

97.391

0.374

Multiple sequence alignment