Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG65_RS23870 Genome accession   NZ_CP010228
Coordinates   4584602..4585234 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain S3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4579602..4590234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG65_RS23845 (RG65_22625) yhfG 4579734..4579901 (+) 168 WP_000736862.1 YhfG family protein -
  RG65_RS23850 (RG65_22630) fic 4579891..4580493 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  RG65_RS23855 (RG65_22635) pabA 4580525..4581088 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  RG65_RS23860 (RG65_22640) argD 4581174..4582394 (+) 1221 WP_000963796.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG65_RS23865 (RG65_22645) yhfK 4582461..4584551 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  RG65_RS23870 (RG65_22650) crp 4584602..4585234 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG65_RS23880 (RG65_22660) yhfA 4585536..4585940 (+) 405 WP_001148908.1 OsmC family protein -
  RG65_RS23885 (RG65_22665) prkB 4585995..4586864 (-) 870 WP_001274680.1 phosphoribulokinase -
  RG65_RS23890 (RG65_22670) yheU 4586918..4587136 (-) 219 WP_000907085.1 YheU family protein -
  RG65_RS23895 (RG65_22675) yheT 4587130..4588152 (-) 1023 WP_000057356.1 hydrolase -
  RG65_RS23900 (RG65_22680) yheS 4588152..4590065 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=118326 RG65_RS23870 WP_000242755.1 4584602..4585234(-) (crp) [Escherichia coli strain S3]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=118326 RG65_RS23870 WP_000242755.1 4584602..4585234(-) (crp) [Escherichia coli strain S3]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467