Detailed information NTG0118171

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KHU1_RS15450
• Genome accession: NZ_CP007242
• Coordinates: 3237453..3238616 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus amyloliquefaciens KHG19
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3232453..3243616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KHU1_RS15420 (KHU1_3010)	-	3232717..3233136 (-)	420	WP_042635530.1	TIGR03826 family flagellar region protein	-
KHU1_RS15425 (KHU1_3011)	comFC	3233210..3233899 (-)	690	WP_197061611.1	phosphoribosyltransferase family protein	Machinery gene
KHU1_RS15430 (KHU1_3012)	-	3233905..3234189 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
KHU1_RS15435 (KHU1_3013)	comFA	3234247..3235632 (-)	1386	WP_042635531.1	DEAD/DEAH box helicase	Machinery gene
KHU1_RS15440 (KHU1_3014)	-	3235741..3236589 (-)	849	WP_007407483.1	DegV family protein	-
KHU1_RS15445 (KHU1_3015)	degU	3236687..3237376 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KHU1_RS15450 (KHU1_3016)	degS	3237453..3238616 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KHU1_RS15455 (KHU1_3017)	-	3238839..3239486 (+)	648	WP_007614107.1	YigZ family protein	-
KHU1_RS15460 (KHU1_3018)	-	3239491..3240711 (+)	1221	WP_020956419.1	LCP family protein	-
KHU1_RS15465 (KHU1_3019)	-	3240818..3241894 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
KHU1_RS15470 (KHU1_3020)	tuaH	3242027..3243223 (-)	1197	WP_042635532.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=118171 KHU1_RS15450 WP_007407484.1 3237453..3238616(-) (degS) [Bacillus amyloliquefaciens KHG19]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=118171 KHU1_RS15450 WP_007407484.1 3237453..3238616(-) (degS) [Bacillus amyloliquefaciens KHG19]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCTTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTGATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
ATCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951