Detailed information NTG1170413

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACLV7W_RS01090
• Genome accession: NZ_OZ217346
• Coordinates: 221931..222941 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090628.1
• Uniprot ID: F9HAD8
• Organism: Streptococcus mitis isolate S. mitis D22
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 216931..227941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7W_RS01065 (SMID22_02140)	folP	217644..218618 (+)	975	WP_261034206.1	dihydropteroate synthase	-
ACLV7W_RS01070 (SMID22_02150)	-	218620..219930 (+)	1311	WP_411865274.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
ACLV7W_RS01075 (SMID22_02160)	folE	219923..220477 (+)	555	WP_411865275.1	GTP cyclohydrolase I FolE	-
ACLV7W_RS01080 (SMID22_02170)	folK	220520..221332 (+)	813	WP_411865276.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
ACLV7W_RS01085 (SMID22_02180)	-	221377..221694 (-)	318	WP_000886035.1	DUF960 domain-containing protein	-
ACLV7W_RS01090 (SMID22_02190)	ccpA	221931..222941 (+)	1011	WP_001090628.1	catabolite control protein A	Regulator
ACLV7W_RS01095 (SMID22_02200)	-	222993..223955 (-)	963	WP_411865277.1	asparaginase	-
ACLV7W_RS01100 (SMID22_02210)	-	224021..225412 (+)	1392	WP_411865278.1	Cof-type HAD-IIB family hydrolase	-
ACLV7W_RS01105 (SMID22_02220)	-	225597..226049 (-)	453	WP_000079148.1	universal stress protein	-
ACLV7W_RS01110 (SMID22_02230)	-	226211..226504 (+)	294	WP_261078123.1	hypothetical protein	-
ACLV7W_RS01115 (SMID22_02240)	-	226660..227874 (+)	1215	WP_000666457.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37155.16 Da
• Isoelectric Point: 5.3350

>NTDB_id=1170413 ACLV7W_RS01090 WP_001090628.1 221931..222941(+) (ccpA) [Streptococcus mitis isolate S. mitis D22]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQVSRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1170413 ACLV7W_RS01090 WP_001090628.1 221931..222941(+) (ccpA) [Streptococcus mitis isolate S. mitis D22]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACGGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACTCGTAAAAAAGTGCTTGAGGTGATTGATCGTTTGGATTACCGTCCAAATG
CTGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTGGTGATCCCAAATATTACCAATGGCTATTTCTCA
ACGCTTGCTAAAGGGATTGACGATATCGCTGAAATGTACAAGTACAATATCGTCCTTGCAAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAGGTGGATGGTATTATCTTTATGGGCTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCAGGAACAGTAGATGTGGAACACCAGCTTCCAAGT
GTTAATATTGACTACAAACAAGCAACGATTGATGCAGTGACCTACCTTGCTAAAGAGAACGAGCGCATTGCTTTCGTTAG
TGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGGATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGATGGCTATGCCTTGGCAGAACGCTTGATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTGTCAGTACC
AGAAGAATTTGAAATCATTACTAGTGATGATTCACAAGTCTCACGCTTTACCCGCCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGCATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGCCGTTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: F9HAD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.238	100	0.952
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.222	99.405	0.887
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568