Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACLV7Q_RS04270 Genome accession   NZ_OZ217341
Coordinates   856151..857500 (+) Length   449 a.a.
NCBI ID   WP_176139155.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 851151..862500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS04245 (SMIC22_08260) coaB 851271..851960 (-) 690 WP_218757735.1 phosphopantothenate--cysteine ligase -
  ACLV7Q_RS04250 (SMIC22_08270) - 852193..853863 (+) 1671 WP_218757736.1 formate--tetrahydrofolate ligase -
  ACLV7Q_RS04255 (SMIC22_08280) - 853985..854137 (-) 153 WP_218757737.1 hypothetical protein -
  ACLV7Q_RS04260 (SMIC22_08290) mutY 854223..855398 (+) 1176 WP_218757738.1 A/G-specific adenine glycosylase -
  ACLV7Q_RS04265 (SMIC22_08300) micA 855454..856158 (+) 705 WP_050259789.1 response regulator YycF Regulator
  ACLV7Q_RS04270 (SMIC22_08310) micB 856151..857500 (+) 1350 WP_176139155.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7Q_RS04275 (SMIC22_08320) vicX 857502..858311 (+) 810 WP_054384038.1 MBL fold metallo-hydrolase Regulator
  ACLV7Q_RS04280 (SMIC22_08330) relB 858402..858644 (+) 243 WP_050223090.1 type II toxin-antitoxin system RelB family antitoxin -
  ACLV7Q_RS04285 (SMIC22_08340) - 858646..858900 (+) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  ACLV7Q_RS04290 (SMIC22_08350) - 859082..860980 (+) 1899 WP_218757739.1 Eco57I restriction-modification methylase domain-containing protein -
  ACLV7Q_RS04295 (SMIC22_08360) - 861090..862040 (+) 951 WP_000658132.1 Abi family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51700.40 Da        Isoelectric Point: 4.9756

>NTDB_id=1170040 ACLV7Q_RS04270 WP_176139155.1 856151..857500(+) (micB) [Streptococcus mitis isolate S. mitis C22]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEEDYELRDLITQSPE
LLLDSQDVNGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1170040 ACLV7Q_RS04270 WP_176139155.1 856151..857500(+) (micB) [Streptococcus mitis isolate S. mitis C22]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCCTATTACTGGAGAATAGACGTGATAATATTCGGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGACTAAATAGTATCCTGTTTTATATGACGGATGGGGT
TCTTGCGACCAATCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGCTGGTTAAAGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAGACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGACGTCAATGGCGAATATCTGAGCCTTCGAGTTCGCTTTGCCTTGATTCGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAGCGCGAACGGAGACTCTTTGTTT
CCAACGTTAGTCATGAGTTACGGACTCCTTTAACCAGTGTGAAATCTTATCTTGAAGCCTTGGATGAGGGAGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAAACCAACCGTATGATGCGCATGGTGACCGACCTCCTTCA
TCTTTCACGGATTGATAACGCCACCAGTCACTTGGATGTGGAACTGATTAACTTCACTGCCTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCTATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCCATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATCTCAGACCATGGTTTAGGCATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTTTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTTTGGGA
CTGTCTATTGCCAAGGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGTAAGGGATCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(98-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

98.886

100

0.989
  vicK Streptococcus mutans UA159

69.652

89.532

0.624

Multiple sequence alignment