Detailed information NTG1169936

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACLV7H_RS01345
• Genome accession: NZ_OZ217340
• Coordinates: 235667..236677 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis isolate S. oralis A22
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 230667..241677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7H_RS01320 (SORA22_02560)	-	230981..232303 (+)	1323	WP_411866155.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
ACLV7H_RS01325 (SORA22_02570)	folE	232284..232838 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
ACLV7H_RS01330 (SORA22_02580)	folK	232997..233818 (+)	822	WP_411866156.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
ACLV7H_RS01335 (SORA22_02590)	-	233811..235094 (+)	1284	WP_411866157.1	DUF308 domain-containing protein	-
ACLV7H_RS01340 (SORA22_02600)	-	235145..235462 (-)	318	WP_045593654.1	DUF960 domain-containing protein	-
ACLV7H_RS01345 (SORA22_02610)	ccpA	235667..236677 (+)	1011	WP_001090635.1	catabolite control protein A	Regulator
ACLV7H_RS01350 (SORA22_02620)	-	236730..237692 (-)	963	WP_045593645.1	asparaginase	-
ACLV7H_RS01355 (SORA22_02630)	-	237758..239143 (+)	1386	WP_411866158.1	Cof-type HAD-IIB family hydrolase	-
ACLV7H_RS01360 (SORA22_02640)	-	239648..241639 (+)	1992	WP_411866159.1	CAP domain-containing protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=1169936 ACLV7H_RS01345 WP_001090635.1 235667..236677(+) (ccpA) [Streptococcus oralis isolate S. oralis A22]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1169936 ACLV7H_RS01345 WP_001090635.1 235667..236677(+) (ccpA) [Streptococcus oralis isolate S. oralis A22]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCGATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGTTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGTAAGAAAACAACGACAGTCGGAGTTGTGATTCCGAACATTACCAATGGTTATTTCTCA
ACACTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTTGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTGAATATCGACTACAAACAAGCAACGATTGATGCCGTGAGCTACCTTCTCAAAGAAAATGAGAAAATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTATAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGCGAGGGCTTGGTCTTTGAATCAAAATACAGCTATGACGATGGCTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCTGCGGGTGTGTTGAATGGTTTGGCTGACCATGGTGTATCTGTGCC
AGAAGAGTTTGAAATCATCACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACTACTATTGCCCAAC
CTCTTTATGACCTAGGCGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGCTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568