Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   ACNUEB_RS02345 Genome accession   NZ_OZ197089
Coordinates   425510..427711 (+) Length   733 a.a.
NCBI ID   WP_001807826.1    Uniprot ID   A0AAP7YX23
Organism   Staphylococcus aureus isolate 23S00080-1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 420510..432711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNUEB_RS02305 aroE 420907..421713 (+) 807 WP_000666746.1 shikimate dehydrogenase -
  ACNUEB_RS02310 yhbY 421717..422007 (+) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  ACNUEB_RS02315 nadD 422010..422579 (+) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACNUEB_RS02320 yqeK 422569..423153 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACNUEB_RS02325 rsfS 423154..423507 (+) 354 WP_001088020.1 ribosome silencing factor -
  ACNUEB_RS02330 - 423510..424226 (+) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  ACNUEB_RS02335 comEA 424266..424952 (+) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  ACNUEB_RS02340 - 425044..425505 (+) 462 WP_000439690.1 ComE operon protein 2 -
  ACNUEB_RS02345 comEC 425510..427711 (+) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACNUEB_RS02350 holA 427768..428742 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -
  ACNUEB_RS02355 rpsT 428787..429038 (-) 252 WP_001274017.1 30S ribosomal protein S20 -
  ACNUEB_RS02360 lepA 429384..431207 (+) 1824 WP_000368338.1 translation elongation factor 4 -

Sequence

Protein


Download         Length: 733 a.a.        Molecular weight: 84968.25 Da        Isoelectric Point: 10.0424

>NTDB_id=1169180 ACNUEB_RS02345 WP_001807826.1 425510..427711(+) (comEC) [Staphylococcus aureus isolate 23S00080-1]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNPQFNERVQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVIDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFVFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGLLSNLIFVPYYSIILFPLSILFFITSHFIVGLMPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVINDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGELEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNVKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYGNASGL

Nucleotide


Download         Length: 2202 bp        

>NTDB_id=1169180 ACNUEB_RS02345 WP_001807826.1 425510..427711(+) (comEC) [Staphylococcus aureus isolate 23S00080-1]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATCCTCAGTTTAATGAGCGTGTTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAGATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTATTGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGTCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGAATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTCTTAATTTATCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCAAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAGCTATTAGCATTTGTATTTATAATTATGTTTATTTTGAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTATTATCTAATTTGATTTTTGTACCATACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAATGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTAATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAATTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTATAACGTTAAACTTATGGATGTAAGGCAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTTCTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGAAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGCCAACAAAACGGTCAAGTTACAATAGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(183-441)

Metallo-beta-lactamase superfamily (Lactamase_B)

(474-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Staphylococcus aureus N315

98.226

100

0.982
  comEC Staphylococcus aureus MW2

97.817

100

0.978

Multiple sequence alignment