Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG48_RS02980 Genome accession   NZ_CP010170
Coordinates   591284..591916 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain H6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 586284..596916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG48_RS02955 (RG48_02780) yhfG 586416..586583 (+) 168 WP_000736862.1 YhfG family protein -
  RG48_RS02960 (RG48_02785) fic 586573..587175 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  RG48_RS02965 (RG48_02790) pabA 587207..587770 (+) 564 WP_000601856.1 aminodeoxychorismate synthase component 2 -
  RG48_RS02970 (RG48_02795) argD 587856..589076 (+) 1221 WP_000963787.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG48_RS02975 (RG48_02800) yhfK 589143..591233 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RG48_RS02980 (RG48_02805) crp 591284..591916 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG48_RS02990 (RG48_02815) yhfA 592218..592622 (+) 405 WP_001148910.1 OsmC family protein -
  RG48_RS02995 (RG48_02820) prkB 592677..593546 (-) 870 WP_001274680.1 phosphoribulokinase -
  RG48_RS03000 (RG48_02825) yheU 593600..593818 (-) 219 WP_000907085.1 YheU family protein -
  RG48_RS03005 (RG48_02830) yheT 593812..594834 (-) 1023 WP_000057379.1 hydrolase -
  RG48_RS03010 (RG48_02835) yheS 594834..596747 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=116892 RG48_RS02980 WP_000242755.1 591284..591916(-) (crp) [Escherichia coli strain H6]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=116892 RG48_RS02980 WP_000242755.1 591284..591916(-) (crp) [Escherichia coli strain H6]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467