Detailed information NTG0116240

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STAB902_RS00615
• Genome accession: NZ_CP007041
• Coordinates: 99278..99712 (+)
• Length: 144 a.a.
• NCBI ID: WP_002992738.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes STAB902
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 94278..104712

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STAB902_RS00585 (STAB902_00610)	-	95947..96312 (+)	366	WP_002986560.1	DUF1033 family protein	-
STAB902_RS00590 (STAB902_00615)	comYA	96405..97343 (+)	939	WP_011054114.1	competence type IV pilus ATPase ComGA	Machinery gene
STAB902_RS00595 (STAB902_00620)	comYB	97279..98313 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
STAB902_RS00600 (STAB902_00625)	comYC	98315..98641 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
STAB902_RS00605 (STAB902_00630)	comGD	98616..99044 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
STAB902_RS00610 (STAB902_00635)	comGE	99001..99285 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
STAB902_RS00615 (STAB902_00640)	comYF	99278..99712 (+)	435	WP_002992738.1	competence type IV pilus minor pilin ComGF	Machinery gene
STAB902_RS00620 (STAB902_00645)	comGG	99696..100022 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
STAB902_RS00625 (STAB902_00650)	comYH	100120..101073 (+)	954	WP_011054117.1	class I SAM-dependent methyltransferase	Machinery gene
STAB902_RS00630 (STAB902_00655)	-	101132..102328 (+)	1197	WP_010921803.1	acetate kinase	-
STAB902_RS00635 (STAB902_00660)	-	102529..102837 (+)	309	WP_011054118.1	hypothetical protein	-
STAB902_RS00640 (STAB902_00665)	proC	102920..103690 (-)	771	WP_002992745.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16645.27 Da
• Isoelectric Point: 10.2526

>NTDB_id=116240 STAB902_RS00615 WP_002992738.1 99278..99712(+) (comYF) [Streptococcus pyogenes STAB902]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=116240 STAB902_RS00615 WP_002992738.1 99278..99712(+) (comYF) [Streptococcus pyogenes STAB902]
TTGAGTAAACAATTAAGTAATATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGCTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396