Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG38_RS15110 Genome accession   NZ_CP010145
Coordinates   2858661..2859293 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain D5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2853661..2864293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG38_RS15080 (RG38_14280) yheS 2853830..2855743 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  RG38_RS15085 (RG38_14285) yheT 2855743..2856765 (+) 1023 WP_000057405.1 hydrolase -
  RG38_RS15090 (RG38_14290) yheU 2856759..2856977 (+) 219 WP_000907085.1 YheU family protein -
  RG38_RS15095 (RG38_14295) prkB 2857031..2857900 (+) 870 WP_001274680.1 phosphoribulokinase -
  RG38_RS15100 (RG38_14300) yhfA 2857955..2858359 (-) 405 WP_001148908.1 OsmC family protein -
  RG38_RS15110 (RG38_14310) crp 2858661..2859293 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG38_RS15115 (RG38_14315) yhfK 2859344..2861434 (+) 2091 WP_021548870.1 YccS/YhfK family putative transporter -
  RG38_RS15120 (RG38_14320) argD 2861501..2862721 (-) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG38_RS15125 (RG38_14325) pabA 2862807..2863370 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  RG38_RS15130 (RG38_14330) fic 2863402..2864004 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  RG38_RS15135 (RG38_14335) yhfG 2863994..2864161 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=116180 RG38_RS15110 WP_000242755.1 2858661..2859293(+) (crp) [Escherichia coli strain D5]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=116180 RG38_RS15110 WP_000242755.1 2858661..2859293(+) (crp) [Escherichia coli strain D5]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment